The anti-diuretic hormone is the full form of ADH. It is also called Arginine Vasopressin (AVP) and has a half-life of 16-24 minutes. It is a peptide pro-hormone encoded by the AVP gene and further activated to AVP. This activated form moves through the axon in the posterior pituitary and is released through vesicles. This hormone has two significant functions: ADH increases renal re-absorption and constricts arterioles. This increases peripheral vascular resistance, increasing arterial blood pressure. Other functions include pair bonding, sexual motivation, social behaviour, and maternal responses to stress. ADH is also involved in cardiomyocyte differentiation and in maintaining heart muscle homeostasis.
Regulation of the amount of water.
Maintain water metabolism by collectively working with baroreceptors and osmotic sensors.
Water reabsorption and production of concentrated urine.
Balance blood composition.
1-5pg/mL (picograms per millilitre) is the normal ADH level.
This may lead to nausea, headaches and vomiting. In extreme cases, coma and seizures can occur.
Epilepsy, brain trauma, tuberculosis, AIDS, or surgery can increase the levels of ADH.
There are various ways to this:
Proper sleep schedule
Regulating stress level
Sufficient water intake
Balanced diet intake and avoiding junk food items
Avoiding non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin
Avoiding morphine or nicotine
The causes of low ADH levels include:
Excessive water intake
Damaged pituitary gland or hypothalamus
Diabetes insipidus might result from any trauma, tumour, trauma, or inflammation of the pituitary gland.