The anti-diuretic hormone is the full form of ADH. It is also called Arginine Vasopressin (AVP) and has a half-life of 16-24 minutes. It is a peptide pro-hormone encoded by the AVP gene and further activated to AVP. This activated form moves through the axon in the posterior pituitary and is released through vesicles. This hormone has two significant functions: ADH increases renal re-absorption and constricts arterioles. This increases peripheral vascular resistance, increasing arterial blood pressure. Other functions include pair bonding, sexual motivation, social behaviour, and maternal responses to stress. ADH is also involved in cardiomyocyte differentiation and in maintaining heart muscle homeostasis.
Regulation of the amount of water.
Maintain water metabolism by collectively working with baroreceptors and osmotic sensors.
Water reabsorption and production of concentrated urine.
Balance blood composition.