Antibiotic - Definition, Types, Side Effects, Discovery, Do's & Don'ts

Antibiotic - Definition, Types, Side Effects, Discovery, Do's & Don'ts

Edited By Irshad Anwar | Updated on Oct 04, 2024 10:31 AM IST

Antibiotics are medications that combat bacterial infections and play an essential role in modern health care. They target specific functions within bacteria, inhibit the bacteria's growth, or kill the bacteria. The topic of Antibiotics falls under Biology under the chapter Microbes in Human Welfare, the student learns of the different kinds of antibiotics, for example, penicillin, and tetracycline, and the various applications of the treatment of infection. It is one of the most important topics in NEET and JEE preparation as questions regarding antibiotic classification, their names, and probable side effects often arise in entrance exams. In mastering this topic, the student not only helps themself during exams but also puts in the critical position for antibiotics regarding health and medication.

What Are Antibiotics

Antibiotics are drugs specifically tailored for combating bacterial infections in humans and animals. It works by either killing these bacteria or blocking their multiplication, hence in high demand through modern medicine. When asking what are antibiotics, it's important to recognize that they come in various forms, including pills, injections, and topical applications.

  • The proper understanding of antibiotics' names and their class is very vital for the treatment process to be effective.
  • Understanding what are antibiotics is crucial for effective treatment, as they do not work against viral infections like the flu or common cold.
  • It is essential to know what are antibiotics and to use them responsibly to prevent antibiotic resistance, which can make future infections harder to treat.

Antibiotics Definition

  • Definition of Antibiotics refers to chemicals that can kill or stop bacteria development and are a crucial part of medical treatment.
  • Several varieties of drugs employed for humans and animals by antibiotics definition are meant to fight bacterial infections.
  • Understanding the antibiotics definition is important to recognize if such an antibiotic is effective against a certain pathogen but is ineffective against viruses.
  • In the context of the health sector, the antibiotics definition underscores the need for prudent use to avert the development of resistance.
  • The antibiotics are also defined according to their mechanism of action and spectrum of activity.

Antibiotics Names

Antibiotics examples include a wide range of medications that are used to treat bacterial infections effectively. Antibiotics are crucial medications used to treat bacterial infections and some parasitic diseases. They function by either killing bacteria or inhibiting their growth, making them essential in modern medicine. Below is a table listing various antibiotics names along with their classifications and common uses.

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Antibiotic Name
Class
Common Uses
Amoxicillin
Penicillin
Treats respiratory infections, ear infections
Ciprofloxacin
Fluoroquinolone
Treats urinary tract infections, bacterial diarrhoea
Doxycycline
Tetracycline
Treats acne, respiratory infections, Lyme disease
Azithromycin
Macrolide
Treats respiratory infections, STIs
Cefalexin
Cephalosporin
Treats skin infections, UTIs
Metronidazole
Nitroimidazole
Treats anaerobic bacterial infections
Gentamicin
Aminoglycoside
Treats severe bacterial infections
Clindamycin
Lincosamide
Treats skin and soft tissue infections
Sulfamethoxazole/Trimethoprim
Sulfonamide
Treats UTIs, respiratory infections
Vancomycin
Glycopeptide
Treats serious Gram-positive infections

These antibiotics names represent a variety of classes and are used to combat different types of bacterial infections effectively. Proper use of antibiotics is vital to minimize resistance and ensure their continued efficacy in treating infections. Understanding what are antibiotics can help patients make informed decisions about their health and recognize the importance of completing prescribed treatments.

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History Of Antibiotic

In 1910 the first antibiotic, salvarsan was developed by scientist Paul Ehrlich. Salvarsan antibiotics are made up of arsenic compounds. This antibiotic is used as a remedy for syphilis disease. But in 1928 a true antibiotic was discovered by Alexander Fleming, named penicillin.

Discovery Of Antibiotic

Alexander Fleming discovered this antibiotic accidentally, when he was doing their work he found mould preventing growth of staphylococcus aureus by producing such type of chemical compound; after that he studied and identified the chemical compound and he discovered a novel penicillin antibiotic. So, he formed this penicillin with the help of bacteria and fungi.

Father Of Antibiotic

Selman Abraham Waksman is the father of antibiotics and he discovered 20 natural antibiotics including streptomycin. Streptomycin is effective against tuberculosis disease.

Antibiotics Classification

Antibiotics are classified based on their mechanism of action, spectrum of activity, and chemical structure. Understanding the antibiotics classification of antibiotics is essential for selecting the appropriate treatment for bacterial infections. Below is a table that outlines various antibiotics classifications, and examples.

Antibiotic Class
Examples
Mechanism of Action
Penicillins
Amoxicillin, Penicillin G
Inhibit cell wall synthesis
Cephalosporins
Cefalexin, Ceftriaxone
Inhibit cell wall synthesis
Macrolides
Azithromycin, Erythromycin
Tetracyclines
Doxycycline, Tetracycline
Inhibit protein synthesis
Fluoroquinolones
Ciprofloxacin, Levofloxacin
Aminoglycosides
Gentamicin, Tobramycin
Inhibit protein synthesis
Glycopeptides
Vancomycin
Inhibit cell wall synthesis
Lincosamides
Clindamycin
Inhibit protein synthesis
Sulfonamides
Sulfamethoxazole
Inhibit folic acid synthesis
Carbapenems
Meropenem, Imipenem
Inhibit cell wall synthesis

These antibiotics names represent a diverse range of classes that target bacteria in different ways. Proper classification of antibiotics is crucial for effective treatment and minimizing resistance. Understanding antibiotics names and antibiotics classification helps healthcare professionals make informed decisions in treating infections.

Antibiotics Drugs Name

Antibiotics are a class of drugs used to treat infections caused by bacteria. Some common antibiotics include amoxicillin, ciprofloxacin, and azithromycin, each serving specific medical purposes based on the type of infection. Understanding the names of these antibiotics is crucial for effective treatment and management of bacterial diseases.

Generic Name
Brand Name Examples
Common Uses
Amoxicillin
Amoxil, Augmentin
Treats respiratory infections, ear infections, and urinary tract infections.
Ciprofloxacin
Cipro
Used for urinary tract infections and certain gastrointestinal infections.
Azithromycin
Zithromax
Effective against respiratory tract infections and some sexually transmitted diseases.
Doxycycline
Vibramycin
Commonly used for acne and respiratory infections.
Clindamycin
Cleocin
Treats serious skin infections and some types of pneumonia.

Types of antibiotics are essential in understanding how to effectively treat various bacterial infections. Each antibiotic type targets specific bacteria, making it important to select the right one based on the infection being treated.

Effectiveness Of Penicillin

Generally penicillin is used for the treatment of infection caused by the pathogenic bacteria. Each type of antibiotic is used for specific infection treatment.

It works by two ways, first - it can kill the bacteria and second - by preventing the growth of bacteria.

Types Of Antibiotics

Antibiotics are categorized into several types, each with unique mechanisms of action and use. Understanding the different types of antibiotics is essential for effective treatment of bacterial infections.

Type of Antibiotic
Examples
Common Uses
Penicillins
Amoxicillin, Penicillin
Treats a variety of infections like strep throat and skin infections.
Cephalosporins
Cefalexin, Ceftriaxone
Used for respiratory infections and urinary tract infections.
Tetracyclines
Doxycycline, Minocycline
Commonly treats acne and respiratory infections.
Macrolides
Azithromycin, Erythromycin
Effective against respiratory and skin infections.
Fluoroquinolones
Ciprofloxacin, Levofloxacin
Used for serious bacterial infections, including UTIs.

Types of antibiotics play a crucial role in modern medicine, helping to combat various bacterial infections effectively. Each type is designed to target specific bacteria, making it important to choose the appropriate one based on the infection being treated.

Production Of Antibiotic

Generally, antibiotics are produced by the fermentation process by using bacteria or fungi, and can be synthesized by using chemicals. Antibiotics are produced by the batch fermentation process. Bacteria produce antibiotics as secondary metabolites during their growth.

Steps of production:-

  1. Production of antibiotics by the fermentation process, and

  2. Chemically synthesis of antibiotics.

A. Production of antibiotics by fermentation process

Following are the general steps for the production of antibiotics by the fermentation process.

1. Culture isolation

Isolation of starter culture according to antibiotic production is required. Culture transferred into nutritive media.

2. Fermentation process

Transfer of fermenting material within the batch fermentor and incubation with controlled environment such as temperature, pH, aeration and agitation, and availability of nutrition.

3. Isolation and Purification of antibiotics.

It can be done by the use of water, oil, and organic solvents. For example, pentyl acetate (is an organic solvent) used in the purification of erythromycin antibiotic purification.

4. Packaging

Antibiotics can be packed in the form of a capsule, or tablet and filled within the vials.

B. Chemically synthesis of antibiotics

In the process of chemical production of antibiotics, the only difference is instead of nutritive median and starter culture we use chemicals.

Mode Of Action

Antibiotic affects bacteria in the following ways such as,

1. Inhibition of cell wall synthesis

2. Change in cell membrane potential

3. Inhibits protein synthesis process

4. Inhibits nucleic acid synthesis

5. Inhibits metabolic pathway of bacteria

Uses Of Antibiotics

Antibiotics are crucial medications used to treat various bacterial infections, effectively killing or inhibiting the growth of harmful bacteria. The uses of antibiotics include treating conditions such as pneumonia, urinary tract infections, and skin infections. Understanding the specific uses of antibiotics helps healthcare professionals select the appropriate treatment for their patients.

Antibiotic Class
Examples
Common Uses
Penicillins
Amoxicillin, Penicillin
Treats streptococcal infections, pneumonia, and skin infections.
Cephalosporins
Ceftriaxone, Cephalexin
Used for respiratory tract infections and meningitis.
Tetracyclines
Doxycycline, Tetracycline
Effective against acne, respiratory infections, and STDs.
Macrolides
Azithromycin, Erythromycin
Treats respiratory tract infections and certain STDs.
Fluoroquinolones
Ciprofloxacin, Levofloxacin
Used for UTIs, bronchitis, and severe bacterial infections.

Types of antibiotics encompass a wide range of medications that target different bacteria based on their mechanisms of action. Each type is designed for specific bacterial infections, making it essential to choose the right antibiotic for effective treatment.

Antibiotics Side Effects

Antibiotics can cause a variety of side effects, ranging from mild to severe. Common side effects include nausea, diarrhoea, and allergic reactions such as rashes or more serious conditions like anaphylaxis. Understanding the potential side effects of antibiotics is essential for safe and effective treatment.

Common Side Effects
Description
Nausea
Feeling sick or queasy, often leading to vomiting.
Diarrhea
Loose or watery stools, sometimes accompanied by cramps.
Allergic Reactions
Skin rashes, itching, or severe reactions like anaphylaxis.
Yeast Infections
Overgrowth of yeast in the mouth or vagina following antibiotic use.
Clostridium difficile Infection
A serious condition causing severe diarrhoea and abdominal pain.

Types of antibiotics can lead to different side effects based on their classification and mechanism of action. Knowing the specific types of antibiotics helps in anticipating potential adverse reactions during treatment.

Tips, Tricks, and Strategies to Prepare for Antibiotics

To effectively study the topic of Antibiotics: Types, Side Effects, Do's & Don'ts, consider these strategies:

Tips and Tricks
Mnemonic
Understand the classifications of antibiotics and their mechanisms.
CLASS (Classify, Learn Antibiotic Structures and Side effects)
Use flashcards to memorize the types and examples of antibiotics.
FLASH (Flashcards Lead to Active Study Habits)
Create a summary chart of side effects and dos & don'ts.
CHART (Concise Help for Antibiotic Review and Testing)
Practice MCQs to reinforce knowledge and application.
PRACTICE (Practice Regularly And Create Testing Insights for Excellence)

Weightage of Antibiotics in Different Entrance Exams

Knowing the weightage of this topic helps prioritize your study efforts. Here’s how it is weighted across various entrance exams:

Entrance Exam
Weightage (%)
5-10%
3-5%
4-6%
6-8%
2-4%

Types of Questions Asked on the Topic Antibiotics in Different Exams

Familiarizing yourself with the types of questions can help you prepare more effectively. Here’s a summary of the types of questions that may be asked across various exams:

Entrance Exam
Types of Questions
NEET
Conceptual questions, case studies
JEE Main
Multiple-choice questions on mechanisms
JEE Advanced
Analytical problems, application-based queries
AIIMS
Short answer questions, scenarios
UPSC
Descriptive questions on antibiotic usage and resistance

By utilizing these tips and understanding the exam weightage and question types, you can enhance your preparation for the topic of Antibiotics.

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Frequently Asked Questions (FAQs)

1. Which are the ways for synthesis of antibiotics?

There are two ways of antibiotic synthesis; 1. Antibiotic production by  bacterial fermentation process and 2. Chemically synthesis of antibiotics.

2. Who discovered a true antibiotic and gave their name?

A true antibiotic was discovered by Alexander Fleming and it is named as penicillin.

3. Who is the father of antibiotics and why?

Selman Abraham Waksman is the father of antibiotics, because he discovered 20 most important antibiotics including streptomycin and all antibiotics are synthesized by natural process.

4. What is the meaning of antibiotics?

The word antibiotics' name suggests ‘Anti’ means against and ‘Biotic’ means life.

5. What is the effect of antibiotics on microbial cells?

Antibiotics affect bateria by different ways, such as Inhibition of cell wall synthesis, Change in cell membrane potential, Inhibits protein synthesis process, Inhibits nucleic acid synthesis and Inhibits metabolic pathway of bacteria.

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