Difference Between ZIFT And GIFT
What Are Assisted Reproductive Technologies (ART)?
Assisted Reproductive Technologies refer to treatment strategies applied in medicine to treat infertility. The technologies may involve interventions to manipulate eggs, sperm, or embryos to assist individuals and/or couples in achieving pregnancy. ART may be the hope for those individuals or couples who are far from pregnancy due to a bad natural conception process. ZIFT, standing for Zygote Intrafallopian Transfer
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Table Difference Between ZIFT And GIFT
ZIFT | GIFT | |
Procedure Differences | IVF-based; zygote transferred to fallopian tube | Direct transfer of eggs and sperm to the fallopian tube |
Success Rates | ~30-40% | ~20-30% |
Indications | Blocked or damaged fallopian tubes; previous ART failures | At least one functional fallopian tube; no severe male infertility |
Risks and Complications | Invasive; surgical risks; higher cost | Less invasive; potential for natural fertilization complications |
Zygote Intrafallopian Transfer (ZIFT)
This is where a zygote is transferred to a fallopian tube to allow the zygote to implant towards the uterus.
IVF: Eggs are removed from a woman's ovary and are married with a sperm in the laboratory.
Zygote Formation: After sperm has fertilized, the ova form a zygote.
Transfer to fallopian tube: The zygote is then transferred to the fallopian tube using a catheter.
Success rate: Usually 30 to 40 per cent; however, it may vary according to age and other relevant factors.
Ideal candidates: candidates with either blockage or damage of fallopian tubes or failed other methods of A.R.T.
Merits: better control over the process of fertilization; tubal problems can be avoided
Demerits: an invasive method; that adds up towards a higher cost; surgical recovery of the eggs is required.
Gamete Intrafallopian Transfer (Gift)
The gamete intrafallopian transfer (GIFT) procedure involves transferring ova and sperm into the fallopian tubes so fertilization can take place naturally.
Collection of egg and sperm: Ova are collected from the ovaries and sperm is collected from the male.
Direct transfer: Both ova and the sperm are directly transferred into the fallopian tubes using a catheter.
Pregnancy Rates: About 20-30%, depending upon the female's age and cause of infertility.
Ideal Candidates: Women having at least one normal functioning fallopian tube. Women with no severe male infertility problems.
Benefits: Least invasive than ZIFT; more natural process of fertilization.
- Limitations: needs at least one functioning fallopian tube; Less control in the process of fertilization.
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Frequently Asked Questions (FAQs)
ZIFT is where a fertilized zygote is injected into the fallopian tube. GIFT is where both ova and sperm are injected into the fallopian tube for fertilization in the body.
ZIFT is generally slightly more successful (~ 30-40%) than GIFT as its rate of success is about 20-30%, both assuming that they vary individually with patients.
In ZIFT, the ovum is fertilized outside the body, and the resulting zygote is transferred into the fallopian tube where it can implant naturally.
Good candidates for GIFT are those women that have, at least one healthy fallopian tube and their partner has no significant issue in respect of sperm count and quality so that fertilization can occur through the normal process of fertilization.
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