The nervous system is a complex network of nerves and cells that transmit signals to and, at all places and times, correspond with other parts of the body. It regulates and collaborates the functions of the body which are related to each other, such as the movement and sensation of some cognitive functions among others. Understanding how the nervous system functions is important for one to appreciate the mechanisms through which different organisms respond to stimuli and how such internal functions maintain proper homeostasis.
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A nerve impulse is an electrical wave that sweeps down the length of a neuron. These impulses are how the nervous system communicates as the waves are how the information can travel to and from the body, through the brain and spinal cord. They allow for anything from a muscle to contract to perception.
The neurones are the basic building blocks of the nervous system, particularly specialized for the communication of nerve impulses. The different parts primarily constituting one single neuron are described as follows.
Cell Body (Soma): It contains the nucleus and other organelles that maintain the health and functioning of the neurone.
Dendrites: The branches are supported extensions, specifically those that allow the receiving of signals by activity conducted through neurone transmissions towards the cell body.
Axon: The second type of long and thin cellular projection that conducts impulses away from the cell body towards the neurons or the effectors.
Nodes of Ranvier: gaps in between the myelin sheath, the action potentials will cause the signal to jump along the axon quickly.
The generation of a nerve impulse includes a series of electrical changes across the membrane of the neuron. The resting neuron initiates the process, and subsequently, several unique phases occur as an impulse is transmitted.
The voltage across the neuronal membrane in the neuron is not conducting an impulse.
Average Value: -70 mV.
Ion Distribution: Outside the neuron, there is a high concentration of Na+; while the inside the neuron contains a high concentration of K+.
Depolarisation: opening of Na+ channels and entry of Na+ make the membrane potential positive.
Repolarisation: The opening of K+ channels and the exit of K+ make the potential negative.
Hyperpolarisation: a momentary increase in negativity before the membrane potential returns to the resting potential.
Refractory Period: A period in which the neuron is not able to initiate another action potential
After the nerve impulse is initiated, it needs to be conducted through the length of the neuron to properly send the message. A nerve impulse can be conducted down the length of a neuron in one of two ways, which depends on whether a neuron is myelinated or un-myelinated.
Happens in myelinated neurons.
Action potential jumps from one Node of Ranvier to the other.
Raises the speed of impulse induction
Happens in un-myelinated neurons.
Action potentials propagate along the axon without decremental
The generation of the nerve impulse is an organized process of electrical changes across the membrane of the neuron. It is a process that initiates with the smallest and moves across all the degrees before a neuron is ready to send an electrical signal.
Presynaptic Neuron: Neuron sending the signal.
Synaptic Cleft: Gap between neurons.
Postsynaptic Neuron: The neuron receiving the signal.
When the action potential reaches the axon terminal.
When Ca2+ enters through calcium channels.
The neurotransmitters are released by the vesicles into the synaptic cleft.
The neurotransmitters bind with the receptors present on the postsynaptic membrane.
The ion channels either open to lead to the depolarisation or hyperpolarisation of the postsynaptic neuron.
The two types of neurotransmitters are:
Examples are Glutamate and acetylcholine.
Promote depolarisation and action potential generation.
Examples are GABA and glycine.
Induce hyperpolarisation, preventing action potential.
Temperature: Higher temperatures increase speed.
Axon Diameter: Larger diameters conduct faster.
Myelination: Myelinated axons conduct impulses more rapidly.
A nerve impulse is an electrical message passed along neurons. Originally, the impulse is generated at the end of the nerve. This impulse is known as an action potential that triggers an electric flow, which in turn triggers the generation of a wave of action potential.
Nerve impulses are carried by neurons through both electrical and chemical processes. When an impulse reaches the terminal end of the axon, the neuro-impulse releases neurotransmitters into the synaptic cleft—which facilitates carrying the impulse to another neuron.
The myelin sheath is a fatty insulator that envelops the axon of some neurons. It speeds nerve impulse conduction because the action potential conducts from one Node of Ranvier to that of the next in "a jumping" way. These are called saltatory conduction.
Nerve impulses are mostly conducted across synapses by transmitting neurotransmitter release. However, if an action potential were to reach an axon terminal, it would depolarise the membrane and cause the calcium channels that feed upon it to open.
Following the opening of voltage-sensitive calcium channels, the calcium ions will flow and give rise to the release of neurotransmitters from synaptic vesicles to the synaptic cleft. The neurotransmitters bind to the receptors on its membrane, therefore either depolarising or hyperpolarising that membrane.
Most neurotransmitters by which the nerve impulse propagates are made up of acetylcholine (ACh), dopamine, serotonin, glutamate, and gamma-aminobutyric acid, which helps maintain the balance in muscle control, mood, memory, and thinking.
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