The human excretory system is an important physiological system, responsible for carrying out an activity of the disposal of waste products and excess substances from the circulatory bloodstream. This helps to keep the constancy of the internal environment of the body. This consists of four organs: the kidneys, the ureters, the urinary bladder, and the urethra, all functioning together in blood filtration and the resulting urine production and its elimination from the body.
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Excretion is critical to homeostasis since it restores the conditions for the body's interior. Conditions for the volume and composition of body fluids, which in turn establishes blood pressure, electrolyte balance, and acid-base balance are thus maintained with the exact conditions needed to function at the cellular and consequently the health levels.
The human excretory system contains important parts with varied excretory functions.
The kidneys are complex organs with several distinct structures, each serving a specific function in the filtration and excretion process:
Tough, fibrous outer layer that serves to protect the kidney.
The outer region of the kidney contains glomeruli and convoluted tubules.
Site of ultrafiltration and initial stages of urine formation.
The inner region consists of renal pyramids and renal columns.
It contains the loops of Henle and collecting ducts.
Triangular-shaped structures within the medulla.
It contains nephron loops and collecting ducts that transport urine to the calyces.
Bands of cortical tissue that separate the renal pyramids.
Provide support for the passage of blood vessels through the kidney.
The microscopic functional units of the kidney. Each nephron is made up of a renal corpuscle and renal tubule.
There are approximately 1 million nephrons per kidney.
It is made up of glomerulus and Bowman's capsule.
It is the first site of blood filtration.
A network of capillaries in which the blood filtration takes place.
It is enclosed by Bowman's capsule.
A cup-like structure that surrounds the glomerulus, collects the filtrate from the blood.
The first segment is for the renal tubule.
Reabsorbs water, ions and nutrients back from the filtrate.
The U-shaped part of the renal tubule extends into the medulla.
Responsible for concentrating urine by reabsorbing water and salt.
The last segment of the renal tubule is before the collecting duct.
Further reabsorption and secretion of ions.
Ducts receive urine from several nephrons.
Transport urine to the renal pelvis.
A funnel-shaped cavity collects urine from collecting ducts.
Channels urine into the ureter.
Supplies the kidney with blood.
Branches further into smaller arterioles, which service the glomerulus
Drains into the inferior vena cava while it conveys deoxygenated blood from the kidney.
Muscular tubes that connect kidneys to the urinary bladder.
The conveyance of urine from the kidneys to the bladder.
A hollow, muscular organ located in the pelvis.
Stores urine until it is eliminated.
Tube extending from the bladder to the outside of the body.
Involved in the elimination of urine.
The net process of urine formation comprises filtration, reabsorption, and secretion. This occurs in the kidneys.
Blood enters the glomerulus; water and solutes get filtered into Bowman's capsule.
Filtration is driven by blood pressure.
Essential substances like glucose, amino acids, and ions get reabsorbed into the blood.
Basically in the proximal convoluted tubule.
Plays a significant role in the reabsorption process of important nutrients and water balance.
The secretion of waste products hydrogen ions, potassium, and some drugs—into the tubule.
This contributes to excess unwanted compounds that are eliminated from the blood.
Kidney functions are mainly regulated through hormones and specific structures to maintain the overall water balance of body fluids and homeostasis.
ADH: increases the amount of water reabsorption by kidneys.
Aldosterone: increases the amount of Na+ reabsorption and K+ secretion.
ANP: decreases the amount of Na+ reabsorption and lowers blood pressure.
Water and Electrolyte balance to sustain osmolarity of blood.
Implores negative feedback loops and hormonal control.
Specialised cells near the glomerulus
Produces renin, thus regulating blood pressure and the filtration rate.
Many disorders can occur in the excretory system, which inhibits the proper clearance of wastes and continued homeostasis.
These are caused by low fluid intake, high salt consumption, and genetics.
Symptoms include severe pain, blood in urine, and frequent urination.
Treatment options are increased fluid intake, medications, and surgery.
Caused by bacterial infection, poor hygiene, and use of a catheter.
Symptoms include painful urination, an urge to urinate frequently, and cloudy urine.
Treatment options are antibiotics and increased fluid intake.
Stages: 1 to 5, based on GFR
Caused by diabetes, blood pressure, glomerulonephritis.
Symptoms include fatigue, swelling, nausea, and decreased urine output.
Treatment options include behavioural changes, medications, dialysis, and kidney transplants.
Major functions include the excretion of waste products, blood pressure, electrolyte balance, and acid-base balance.
Blood enters the kidneys via the renal artery and then it flows into the glomerulus where it gets filtered and wastes are removed. Things needed are reabsorbed into the circulation.
Severe back or side pain, blood in the urine, frequent/painful urination, nausea.
Drink plenty of water; eat a healthy diet; maintain good hygiene.
By GFR, chronic kidney disease is classified into five stages, in ascending order of severity, from mild (Stage 1) to kidney failure (Stage 5).
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