Human Health and Disease

Human Health and Disease

Edited By Irshad Anwar | Updated on Nov 25, 2024 06:53 PM IST

Human health and disease focus on the physical, mental, and social well-being of people. It studies diseases, their causes, and how to prevent or treat them. It also explains how the immune system works and how disorders, infections, and lifestyles affect health. Learning about human health and disease is an important part of biology, as it helps improve the quality of life. The chapter carries a weightage of 5-6% of the total marks in NEET and 3-4% of the weightage of other entrance exams like Paramedical and Nursing.

This Story also Contains
  1. Important Topics of Human Health and Diseases
  2. Overview of the Chapter
  3. What is Health?
  4. What is Disease?
  5. Common Human Diseases
  6. Immunity
  7. Alcohol and Drug Abuse
  8. Human Health and Disease MCQ
  9. Types of Questions and Weightage of Human Health and Disease
  10. Tips, Tricks, and Strategies for Human Health And Disease
  11. Prescribed Books for Human Health and Diseases
Human Health and Disease
Human Health and Disease

Important Topics of Human Health and Diseases

  • Factors affecting Health
  • Types of Diseases
  • Immunity
  • Alcohol and Drug Abuse
  • Important Concepts - Pathogens, Vaccination, Cancer, AIDS

Overview of the Chapter

The "Human Health and Disease" chapter of Class 12 CBSE deals with the concept of health, its importance, and the numerous factors affecting it. The chapter further provides a series of causes of disease and various diseases, including infectious and non-infectious diseases, along with prevention and control. It further explains the immune system with accounts for innate and acquired immunity as well as vaccines. It covers such common human diseases as malaria, cancer, and AIDS, among others, and lifestyle diseases. At the same time, it focuses on good health through balanced diet, hygiene, and exercise.

What is Health?

Health can be defined as a state of well-being where an individual feels body, mind, and social well-being. It is not only the absence of disease but also having the energy and ability to enjoy life to the fullest. Good health is dependent upon healthy nutrition, staying active, getting ample rest, and managing stress. It also has to do with living in a clean environment and avoiding bad habits.

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Factors Affecting Health

Many factors affect our health:

  • Genetic disorders inherited by parents cause deficiency or defects at birth.
  • Infections are conditions brought about by microbes, such as bacteria or viruses.
  • Lifestyle, diet, exercise, sleep, and habits all contribute to fitness or overall good health.

Factors Affecting Physical Health

  • Nutrition: Adequate nutrition fuels body operations.
  • Physical Activity: Exercise keeps your heart healthy, strengthens, and remains flexible.
  • Sleep: This is needed to restore and promote emotional health.
  • Hygiene: Keeps diseases and infections away.

Factors Affecting Mental Health

  • Stress: Chronic stress can lead to anxiety and depression
  • Lifestyle: Diet, exercise, and substance abuse can lead to devastating effects on mental health
  • Trauma: Previous trauma or abuse leads to mental disorders
  • Genetics: Histories of mental illnesses in the family predispose an individual to mental disorders
  • Environment: Lifestyle and chronic illness can affect an individual's mental well-being
  • Brain Chemistry: Mental disorders can result from either balances or imbalances of neurotransmitters.
  • Cognitive Health: Mental activity can contribute to maintaining healthy cognition.

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What is Disease?

A disease is a condition that causes the body or mind to perform abnormally. It results from some form of abnormality in the body, such as an infection, injury, or imbalance. Diseases can be caused by microbes, such as bacteria or viruses, unhealthy habits, or genes passed from parents. Some diseases are short-lived, such as the flu, and others, such as diabetes, last longer. Treatment and prevention also vary according to the disease.

Types of Diseases

Human diseases fall into two categories:

Congenital: A condition that has existed since birth

Acquired: Disease that occurs during a person's lifetime

Basic points about Congenital and Acquired are discussed below:

Congenital

Acquired

  • Conditions which are present since birth due to environmental factors during pregnancy.

  • Diseases which are developed during any stage at personal lifetime and are known as acquired disease

  • Genetic mutation, chromosomal abnormalities, environmental influences and exposure to drugs are causes of congenital diseases.

  • Infection, lifestyle Choices, ageing and immune system dysfunction are some common causes.

  • Down Syndrome, Cystic fibrosis, and congenital heart are some basic examples

  • Diabetes, Tuberculosis, hypertension and cancer are some of the basic examples.

Causes of Diseases

Pathogens are often responsible for the disease. Lifestyle choices, genetic factors and environmental factors are other causes.

  • Pathogens: Bacteria, viruses, parasites and fungi cause infectious diseases. For example, flu virus and tuberculosis.

  • Lifestyle Choices: smoking, poor diet, and lack of exercise and sleep can result in heart disease, diabetes, and obesity.

  • Genetic Factors: Genetic mutations are inherited and can lead to diseases such as cystic fibrosis or sickle cell anaemia.

  • Environmental Factors: Pollution, exposure to hazardous chemicals, and poor living conditions can lead to respiratory diseases, cancers, and other health issues.

Transmission of Diseases

  • Direct Contact: Diseases can be transmitted through direct contact. (For example, flu and chickenpox)

  • Indirect Contact: Diseases are transmitted via contaminated surfaces, objects, or food and water (norovirus or hepatitis A).

  • Vectors: Insects or animals act as a medium of transmission for diseases. They carry pathogens from one host to another. For example, mosquitoes transmit dengue and malaria fever.

  • Transmission via Air: Pathogens present in droplets spread through the air. For example, tuberculosis and COVID-19.

Prevention of Diseases

There is a famous saying, “Prevention is better than cure." There is a lot to do to protect yourself from disease.

  • Healthy Lifestyle: Have a balanced diet, sufficient sleep, and do some physical activities regularly to boost your immune system.

  • Hygiene: There is some minute work to do to reduce the risk of infections. Maintain cleanliness and proper sanitation. Wash your hands regularly before having a meal.

  • Vaccination: Immunise yourself against diseases like polio, influenza and measles by taking a vaccine and building immunity.

  • Eliminate risk factors: avoid exposure to harmful substances such as smoking, and alcohol.

  • Masks: Use masks to avoid pollution and air-borne diseases.

To treat bacterial, viral, and fungal infections, antibiotics, antivirals, and antifungals are used, respectively. Anti-inflammatory medications and painkillers are used to treat symptoms.

Common Human Diseases

The table below lists the common diseases that affect humans:

Disease

Symptoms

Causes

Preventive Measures

Malaria

Fever, chills, sweating, headache, nausea

Plasmodium parasite transmitted by Anopheles mosquitoes

Use insect repellent, mosquito nets, and antimalarial drugs

AIDS

Weak immune system, opportunistic infections, weight loss, fatigue

Human Immunodeficiency Virus (HIV)

Safe sex practices, avoid sharing needles, antiretroviral therapy (ART)

Tuberculosis (TB)

Persistent cough, chest pain, night sweats, weight loss

Mycobacterium tuberculosis bacteria

BCG vaccination, good ventilation, proper treatment of active TB cases


Cancer

Variations by type can include lumps, abnormal bleeding, weight loss, and fatigue

Genetic mutations, lifestyle factors (smoking, diet), environmental exposures

Regular screenings, healthy lifestyle, avoiding carcinogens

Diabetes

Increased thirst, frequent urination, fatigue, and blurred vision

Insufficient insulin production (Type 1) or insulin resistance (Type 2)

Healthy diet, regular exercise, maintaining a healthy weight, and monitoring blood sugar levels


Immunity

The immune system refers to the body's ability to fight off infections by invading viruses or foreign bodies. There are two types, such as.

Innate Immunity

This protection is available from the time of birth and provides barriers to attack by any foreign agent that causes infections. In addition, there are four types:

  • Physical barrier
  • Physiological barrier
  • Cellular barrier
  • Cytokine barrier

Acquired immunity

This type of resistance is directly related to the pathogen, and a person acquires it during his or her lifetime.

Allergies

Allergies occur when the immune system reacts to certain things such as pollen, medicines, food, etc. The human immune system can distinguish between foreign molecules and bodies. However, there are cases when the body beats its cells. As a result, it is harmful to the body and is called an autoimmune disease. A usual example of such a given effect is rheumatoid arthritis.

Cancer

Cancer refers to the uncontrolled and abnormal replication of cells. These cells capture and kill neighbouring tissues, and the continuous proliferation of cancer cells causes metastasis. The basics of cancer are discussed below:

Tumor Type

Description

Characteristics

Causes of Cancer

  • Benign tumour

  • Non- Cancerous and slow-growing tumour

  • Do not spread to the other tissues

  • Genetic mutation

  • Malignant tumour

  • Cancerous and fast-growing tumour. Also, have the capability of metastasis.

  • Spread via blood and lymph to the other organs

  • Radiation, chemical exposure, virus, lifestyle, environmental factors and immune dysfunction.

Alcohol and Drug Abuse

Drug abuse commonly includes cannabinoids, coca alkaloids and opioids. Few medicines can be found in the fungus, especially in flowering plants. Opioid drugs also bind to the opioid receptors present in the human GI tract and the CNS (Central Nervous System). On the other hand, cannabinoids interact with cannabinoid receptors in the brain. Examples of such drugs are hashish, marijuana, and charm.

Human Health and Disease MCQ

Given below are some human health and disease NEET questions:

Which of the following is an example of an autoimmune disease?
a) Malaria
b) Diabetes mellitus
c) Rheumatoid arthritis
d) Tuberculosis
Ans: c) Rheumatoid arthritis

What is the primary cause of AIDS?
a) Bacteria
b) HIV virus
c) Plasmodium
d) Influenza virus
Ans: b) HIV virus

Which cells are responsible for antibody production in the immune system?
a) T-cells
b) B-cells
c) Neutrophils
d) Monocytes
Ans: b) B-cells

The vaccine for tuberculosis is:
a) DPT
b) BCG
c) Polio vaccine
d) Hepatitis vaccine
Ans: b) BCG

Which type of immunity is obtained through vaccination?
a) Natural active immunity
b) Artificial active immunity
c) Natural passive immunity
d) Artificial passive immunity
Ans: b) Artificial active immunity

In malaria, the causative agent affects which cells in humans?
a) Red blood cells
b) White blood cells
c) Liver cells
d) Both a and c
Ans: d) Both a and c

Which of the following diseases is not transmitted by mosquitoes?
a) Dengue
b) Malaria
c) AIDS
d) Chikungunya
Ans: c) AIDS

Types of Questions and Weightage of Human Health and Disease

During the preparation of the exam, there are different types of questions asked in different forms. The table given below contains the different patterns of questions asked in different exams.

Exam Type

Types of Questions Asked

Weightage

CBSE

  • Types of diseases (infectious, non-infectious).

  • Immune system structure and function (innate and adaptive immunity).

  • Vaccination and immunity.

  • Common diseases (malaria, dengue, cancer, HIV/AIDS).

  • Lifestyle-related diseases (diabetes, heart diseases).

5-6%

NEET

  • Structure and function of the immune system (T-cells, B-cells, antibodies).

  • Mechanisms of immunity (humoral and cell-mediated).

  • Types of pathogens (bacteria, viruses, fungi, parasites).

  • Prevention and control of diseases (vaccination, public health measures).

  • Cancer and its types.

  • Drugs and alcohol abuse and their impact on health.

3-4%

Paramedical Exams

  • Impact of diseases on public health.

  • Clinical aspects of infectious diseases and their treatments.

  • Role of the immune system in combating infections.

  • Diagnosis and treatment of lifestyle diseases (e.g., diabetes, cardiovascular diseases).

  • Applications of molecular biology in diagnosing and treating diseases (e.g., PCR, gene therapy).

2-3%

Tips, Tricks, and Strategies for Human Health And Disease

It's hard to remember everything in a single go. We made the entire problem easy. Some of the tricks regarding human health and disease are given below which you can use to memorize the important points.

Types of Diseases

"DIA: Infectious, Autoimmune, Degenerative"

  • D: Infectious diseases (caused by pathogens)

  • I: Autoimmune diseases (immune system attacks the body)

  • A: Degenerative diseases (progressive deterioration of function)

Risk Factors for Disease

"LIFE: Lifestyle, Inherited, Functional, Environmental"

  • L: Lifestyle choices (diet, exercise)

  • I: Inherited factors (genetic predisposition)

  • F: Functional limitations (chronic conditions affecting health)

  • E: Environmental factors (pollution, exposure)

Immune System Components

"B-TEA: B cells, T cells, Eosinophils, Antibodies"

  • B: B cells (produce antibodies)

  • T: T cells (regulate immune responses)

  • E: Eosinophils (combat parasites and allergic reactions)

  • A: Antibodies (proteins that identify and neutralize pathogens)

Preventive Health Measures

"DIVA: Diet, Immunizations, Visits (doctor), Activities (physical)"

  • D: Healthy diet

  • I: Regular immunizations

  • V: Regular doctor visits for check-ups

  • A: Regular physical activity

Chronic Disease Management

"CAMP: Control, Adherence, Monitoring, Prevention"

  • C: Control symptoms (medication and lifestyle)

  • A: Adherence to treatment plans

  • M: Monitoring health status (regular check-ups)

  • P: Preventing complications (education and resources)

Common Infectious Diseases

"VIP: Virus, Infection, Prevention"

  • V: Viral infections (e.g., influenza, COVID-19)

  • I: Bacterial infections (e.g., strep throat, tuberculosis)

  • P: Prevention strategies (handwashing, vaccination)

Lifestyle Changes for Better Health

"HEAL: Healthy Eating, Exercise, Adequate Sleep, Limit Stress"

  • H: Healthy eating habits

  • E: Regular exercise

  • A: Getting enough sleep

  • L: Limiting stress through mindfulness and relaxation

Signs of Illness

"Fever, Pain, Swelling, Fatigue: "

  • F: Fever (indicates infection)

  • P: Pain (may signal injury or illness)

  • S: Swelling (could indicate inflammation)

  • F: Fatigue (may signal underlying health issues)

Prescribed Books for Human Health and Diseases

NCERT Biology textbook class 12 forms the base for learning about Human Health and Diseases. Further extended understanding of the concept can be done through "Trueman's Elementary Biology, Volume 2", which provides all essential explanations with practice questions. Another helpful book is "Pradeep's Biology" which provides proper explanations with solved examples. Other great videos, articles, and practice mock tests are available on the Careers360 website for this chapter.

Also Read

Frequently Asked Questions (FAQs)

1. What are the Key concepts in Human Health and Disease in Chapter?

The key concepts in human health and disease are the types of diseases, common infectious diseases, infections, AIDS, cancer, etc.

2. What are the different ways of transmitting the Human Immunodeficiency Virus?

Different ways of transmitting the virus are through sexual contact, blood transfusions of infected people and the use of one needle for more than one person.

3. What is called the treatment and study of Neoplasms?

The field of neoplasm - benign and malignant research is known as oncology.

4. What are the types of innate immunity?
  • Physical barrier
  • Physiological barrier
  • Cellular barrier
  • Cytokine barrier
5. Name the virus that causes AIDS.

The Human ImmunoDeficiency Virus (HIV) is responsible for causing AIDS. 

6. Write about the types of disease.

Human diseases fall into two categories:

Congenital: A condition that has existed since birth

Acquired: Disease that occurs during a person's lifetime

7. Why is it important to wash hands before eating?

Washing hands before meals protects one from pathogens that may transmit infectious diseases and helps the individual to be much healthier and cleaner.

8. What are the main factors affecting physical health?

Physical health can be influenced by key aspects: nutrition, physical activity, sleep, and hygiene.

9. What is the difference between infectious and non-infectious diseases?

Infectious diseases are Pathogens and contagious from one individual to another. On the other hand, non-infectious diseases are not transmitted from person to person. The latter is mostly caused by genetic or environmental factors and/or the result of bad habits in day-to-day life.

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