It is a type of incomplete dominance of alleles in which the second allele does not hide the first, and instead of fully expressing the predisposition of one allele, intermediate phenotypes of both alleles are observed. Charles Darwin published his theory of evolution in the 19th century; however, the initial study on the laws of heredity was conducted by Gregor Mendel on pea plants.
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He made numerous observations and mathematical interpretations that provided the foundation of modern genetics; laws of Segregation and Independent Assortment. It is important to study incomplete dominance because, besides simple dominant and recessive genes, there are variations in how genes work and appear in things, and it is useful to know more about that. This is important in areas like medicine, agriculture and the study of other aspects of evolution because knowledge of genetic inheritance enables development in disease cure, improvement in food crops and the effort to conserve species
Gregor Mendel also made important experiments using the pea plant as his model with which he laid the great foundation for genetic science. His experiments led to the formulation of two fundamental laws of inheritance:
According to this law of independent assortment, alleles for a particular trait separate during the formation of gametes and gametes get only one allele on this trait from either of the two parents.
Mendel also found that alleles for different genes do not get transmitted together to the next generation, during gamete formation if the two alleles are situated on different chromosomes or if they are far apart on the same chromosome.
These laws based on genotypes such as the shape of a seed, color, and height of the plant have helped in understanding heredity and marked the foundation for genetics as a science.
In the system of inheritance, there is complete dominance in which one allele masks the other allele and there is a dominance series where there is an intergradient of three phenotypes of the two genotypes. In complete dominance, one allele is dominant to another and thus can prevent the other from expression while in incomplete dominance, both alleles and neither is dominant to the other.
Incomplete dominance differs from both complete dominance and codominance in how alleles interact: Incomplete dominance differs from both complete dominance and codominance in how alleles interact:
Complete Dominance
In the heterozygous condition one allele g Completer masks the expression of the second allele g in the genotype. For instance, in Mendel’s pea plants, the yellow seed colour concealed the green colour trait since it is a dominant characteristic whereas the green colour seed is a recessive characteristic.
Codominance
In codominance, both alleles are dominant in the sense that both contribute to the phenotype of the heterozygous individual without the blending. This leads to the genes that code for these two traits being expressed fully, hence the organism will exhibit the particular traits. A well-documented example is blood groups in human beings where the AB group has both A and B antibodies.
A good example of this form of inheritance is a flower colour in snapdragons (Antirrhinum species) where F1 plants are blush-orange coloured flowers and the F2 plants have six different phenotypes, with no dominant phenotype. In this case, the R-genotype represents incomplete dominance over the r-genotype where R stands for the red flower colour and r for the white flower colour. Rr genotypes are considered heterozygous and the plants have pink flowers in the middle of the two extremes, the pure red and white flowers. This case clearly shows that the system of incomplete dominance leads not to the completely dominant or thoroughly recessive relation, but rather to the scales of phenotypic manifestation.
The term incomplete dominance results from alleles in which neither allele has a superior phenotype over the other. This leads to a heterozygous genotype that is that is an equal blend of the two homozygous genotypes. For instance in snapdragons, the R allele for red flowers is codominant with the r allele for white flowers, this is because heterozygous individuals will exhibit pink flowers.
Example: Red Snapdragons, White Snapdragons and Pink Flowers
Genotypes:
Homozygous Red: RR
Homozygous White: rr
Heterozygous Pink: Rr
Phenotypes:
RR: Red flowers
rr: White flowers
Rr: The intermediate phenotype/ transition phase/ grade II is lavender flowers or pink flowers.
When a homozygous red (RR) snapdragon is crossed with a homozygous white (rr) snapdragon, the Punnett square shows: When a homozygous red (RR) snapdragon is crossed with a homozygous white (rr) snapdragon, the Punnett square shows:
R r
R RR Rr
r Rr rr
Genotype Ratio: 1 RR: 2 Rr: 1 rr
Phenotype Ratio: Therefore the R alleles will all paint red and the r alleles paint white.
Genetic Basis: In snapdragons (Antirrhinum species), the L: red allele dominates the L: white allele, but not completely. Dominant and recessive plants came out pink and pure red respectively; the Rr plants showed a pink flower which is an intermediate phenotype.
Illustration:
Explanation: Punnett square for this example would be the crossing involving the resulting alleles of red, pink and white flowers.
Genetic Basis: In Andalusian chickens, the blue allele is an example of complete dominance to the black allele, marked B/b. Purebred chickens with BB genes for body colour are blue, those with a single pair of genes Bb are splash, a mottling of blue and white and those with bb genes are black.
Illustration:
Explanation: This diagram illustrates the dominance and penetrating incompleteness of the pen colour in Andalusian chickens. Human hair texture (curly, wavy, and straight hair)
Genetic Basis: Human hair texture includes the type of hair such as curly, wavy, or straight and this trait arises due to multiple genes and the type of dominance. There are dominant and recessive genes containing CURLY (C), Wavy (W) and straight (S) hair textures combined to give a variability of hair textures.
Illustration:
Explanation: This diagram shows that individuals inherit the combinations of alleles (CC, CW, WW, etc. ) meaning that one will get curly hair if they possess allele ‘CC’ or wavy hair if they possess ‘CW’ or straight hair if they have ‘WW’ and so on.
This means that when the two alleles are present in an organism of a gene, neither of them can effectively suppress the effect of the other. However, the two alleles mix giving rise to a new phenotype which is a combination of the two extreme phenotypes.
Incomplete dominance is said to exist where the heterozygote has an appearance between the two homozygous phenotypes. Codominance hence means that both alleles in the heterozygous condition are dominant, many times manifesting in a phenotype with both traits being observed.
Indeed, incomplete dominance can be mentioned among humans. Some examples are hair type: curly, wavy, straight; and some elements of blood type pathology.
For instance, the colour of the snapdragon flower is red, white or pink petal colour, the feather colour of Andalusian chickens is blue, black or splash and the texture of the hair is curly, wavy or straight.
The phenomenon described the blend of genes as a result of crossbreeding, where Mendel observed that the factor responsible for seed coat colour was incompletely dominant. His observations then formed the basis on which the workings of alleles could be explained as to how they affect the phenotypic characteristics.
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