The spinal cord is a vital part of the central nervous system, extending from the brainstem down through the vertebral column. It acts as a communication highway, transmitting signals between the brain and the rest of the body. The spinal cord also coordinates reflex actions and plays a critical role in maintaining posture and movement. In this article, the spinal cord, anatomy of the spinal cord, functions of the spinal cord, spinal cord nerves and their functions, and spinal cord injuries and disorders are discussed. Spinal Cord is a topic of the chapter Neural Control and Coordination in Biology.
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It is a cylindrically shaped bundle of nerves extending from the brainstem down the vertebral column. It acts as that major pathway through which sensory and motor signals are transmitted between the brain and the rest of the body.
The spinal cord plays a crucial role in synchronising reflexes and movements, like walking and catching, with the transmission of information from the body to the brain. Housed within the protective casement of the vertebral column, it provides the basic functions that underlie simple bodily activities as well as complex motor activities, thus being indispensable to human movement, sensation, and general neurological functioning.
The spinal cord is a cylindrical structure comprising nervous tissue extending from the brainstem through the vertebral column and ending near the first or second lumbar vertebra in adults. However, this may vary a bit from one individual to another.
The length of the spinal cord averages approximately 45 cm (18 inches) in adults.
Its diameter varies along its length, being larger in regions where nerves controlling the limbs originate.
The total vertebral column consists of 33 vertebrae, which encase and protect the spinal cord.
There are 7 cervical, 12 thoracic, 5 lumbar, 5 sacral fused into the sacrum, and 4 coccygeal vertebrae.
Each of these vertebrae forms a part of the bony armour surrounding the fragile spinal cord, thereby protecting it from damage.
The spinal cord is divided into:
That part of the spinal cord in the neck region consists of 8 cervical segments (C1-C8).
This lies in the upper back and consists of 12 thoracic segments, T1-T12.
This lies in the lower back and consists of 5 lumbar segments, L1-L5.
This is part of the pelvis and consists of 5 sacral segments, S1-S5, fused in the sacrum.
The spinal cord is segmented. Each segment is related to a pair of nerve roots arising from the vertebral column.
Number of Segments: 31 in number. 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal.
Each segment gives off nerve roots that arise from the cord and emerge through openings formed by successive vertebrae.
These nerve roots then unite to form peripheral nerves that innervate regions of the body.
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A large variety of functions are carried out within the spinal cord, which includes transmitting nerve signals, controlling pathways of sensation and movement, and providing reflex actions.
It acts as a way of conveying nerve impulses from the brain to the body and vice versa.
The spinal cord relays sensory information it picks up from the peripheral sensory receptors towards the brain for processing.
It receives the motor signals from the brain, triggering an outward flow that initiates muscle and other responses
Information on touch, temperature, pain, and proprioception from the body is transmitted to the brain through the spinal cord via the sensory pathways.
They involve sensory neurons that take signals directly up the spinal cord to the brainstem and higher brain centres for perception.
The motor pathways carry commands from the brain down the spinal cord to motor neurons innervating muscles and glands throughout the body.
It's through this that the communication will allow for both voluntary movements, like walking or reaching, and involuntary actions, like regulating the heartbeat.
Reflex actions are, therefore, responses that are immediate to certain stimuli, not requiring any conscious processes and directly involving the spinal cord.
The examples include protection of the body against damage, maintenance of posture, and regulation of a variety of physiological processes, all without requiring a single input from the brain.
Reflexes are automatic responses to specific stimuli, controlled by simple neural circuits called reflex arcs made up of sensory neurons and interneurons in the spinal cord, as well as motor neurons.
For instance, during the knee jerk reflex, which is also referred to as the patellar reflex, tapping the patellar tendon initiates involuntary stretching of the leg.
Another example is the withdrawal reflex: the hand is suddenly drawn back from a hot surface.
Reflex arcs are essential to survival and day-to-day functioning.
They provide very quick responses on the part of the body to impending dangers or other environmental changes.
Involving the spinal cord directly allows very rapid responses to happen, thereby preventing injury or allowing immediate reactions to occur—critical in maintaining whole bodily function and coordination.
Each of these segments corresponds to a specific pair of spinal nerves supplying different regions of the body. The total overview of the primary spinal nerves and their functions is given below:
C1-C4: The cervical nerves predominantly provide structures for muscles of the neck and respiration. Therefore, the nerves take part in breathing and movements of the head.
C5-C8: These nerves innervate muscles in the shoulders, arms, and hands. They play a very important role in upper limb movements and terms of sensory perception in the line of these parts.
T1-T12: Thoracic nerves innervate the muscles and skin of the thorax and abdomen. They participate in the movements of the chest wall and the abdominal muscle activity, as well as sensitivity in those areas.
L1-L5: Lumbar nerves innervate the lower back, buttocks, thighs, legs, and feet. They are responsible for locomotion and sensibilities in these fields, such as walking, standing, and balance.
S1-S5: These nerves are responsible for the innervation of the pelvis, genitals, buttocks and lower limbs and orchestrate acts like bowel and bladder activity, sexual function, movement and sensibility of the lower extremity.
Coccygeal Nerve (Co1): The coccygeal nerve is the smallest spinal nerve, and it innervates a small area of skin over the coccyx (tailbone).
Trauma or disease can cause spinal cord injuries (SCI), which are divided into two major types: complete and incomplete injuries.
Complete injuries: These occur with a total loss of sensation and motor function below the level of injury. The most common cause is cutting or serious damage to the spinal cord.
Incomplete Injuries: It preserves partial communication between the brain and parts of the body below the site of injury. Sensation and motor function may then be partially preserved, depending on the extent of damage to the spinal cord.
Trauma: This can be caused by everyday events, including road traffic accidents, falls, sporting injuries, and acts of violence.
Disease: All kinds of pathologies may cause spinal cord lesions, such as Tumors, infections, meningitis, and degenerative disorders, especially spinal stenosis.
The spinal cord is prone to many disorders that either diminish its blood flow or harm it directly.
The major spinal cord disorders are:
A case of autoimmune neurologic disorder wherein the immune system acts against the protective myelin sheath covering nerve fibres in the brain and spinal cord. It causes problems in communication between the brain and the rest of the body.
Lou Gehrig's disease is a neurodegenerative process characterized by progressive destruction of nerve cells in the brain and spinal cord. These nerve cells control voluntary muscle movement; hence, their loss leads to the loss of muscle control, consequently resulting in paralysis.
This refers to a congenital condition whereby, before birth, there is an incomplete development of the spinal cord and its covering structures. It generates an extremely vast array of different physical and intellectual disabilities based on severity.
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The spinal cord's main function is the conduction of sensory information from the body towards the brain and motor commands from the brain towards the body. In addition, it coordinates reflexes, some of the fundamental motor responses that do not require brain involvement or involvement.
Common causes of spinal cord injuries include traumatic events like motor vehicle accidents, falls, sports injuries, and acts of violence. Nontraumatic events may be caused by diseases that include spinal cord tumours, infections, degenerative disorders, and others.
The diagnosis of spinal cord injury includes clinical evaluation for imaging tests to visualise damage to the spinal cord; neurological examinations delineate sensory and motor loss below the level of injury.
Grey matter consists mainly of neuronal cell bodies, dendrites, and unmyelinated axons of the spinal cord. It processes and integrates information from sensory and motor components. White matter consists of myelinated axons that form nerve tracts connecting disparate regions of the spinal cord and convey signals between the brain and the body.
Research is being conducted on spinal cord regeneration through various methods to enhance nerve regeneration and regain function, such as stem cell therapy, nerve grafting, and biomaterial scaffolds. In the latest developments, efforts are being made toward inducing axonal growth and enhancing plasticity in the injured spinal cord. That gives hope that shortly, better treatments will be developed, greatly improving outcomes for patients suffering from spinal cord injuries.
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