The life cycle of the virus describes how a virus infects a host cell, replicates, and multiplies to other cells. This is important for reproducing viruses because they cannot reproduce themselves they need some help from a host cell. During the life cycle of a virus, the virus binds to a cell, enters it, uses that cell's machinery to create more viruses, and then releases those new viruses to infect other cells. It's important to about the virus life cycle and virus reproduction represents an important part of biology.
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Viruses are infections that can only replicate inside a host cell. They consist of genetic material in the form of either DNA or RNA, surrounded by a protein coat known as the capsid. An outer lipid envelope may also be present. Viruses differ from all other microorganisms because they completely depend on cellular metabolism for their growth and multiplication.
The virus life cycles have been fundamental in understanding infection, replication, and spread of viruses in the host cell. Such information is important in developing effective antiviral drugs against viruses and vaccines and public health strategies aimed at controlling and preventing viral diseases, improving the burden on global health.
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The attachment of the virus to a host cell is the first step of the life cycle of a virus. This step is selective because only cells with the receptors on their surfaces can be infected by a virus. It is like how only keys that fit into existing locks can be used for opening locks.
The surface proteins of the virus bind very strongly to these receptors. Without this step, the virus cannot get inside the cell or begin viruses production. This determines which organisms or tissues the virus can infect.
After attachment, the virus enters the host another stage of the virus life cycle. The way entry occurs depends on the kind of virus. Some viruses fuse their outer envelope with the host cell membrane, while others are engulfed by the cell through endocytosis.
Others introduce their genetic material through direct injection into the cell. This entry is an important step in the initiation of virus reproduction because it enables the virus to introduce its blueprint of genetic material into the cell, to hijack the machinery of the cell.
Replication is the heart of virus reproduction within the virus life cycle. Once inside the host cell, the viral genetic material gets in control of the machinery of the host cell and starts making copies of itself. Most DNA viruses penetrate the nucleus, using that cell's DNA-replicating enzymes.
The majority of RNA viruses replicate in the cytoplasm. The host cell will have no clue that it is being given orders on what it should do as it goes through the process of producing thousands of copies of the viral genome and all its proteins. This stage ensures that the virus can replicate and produce new infectious particles.
This is the assembly point where newly formed viral genetic material and proteins are combined to form complete viruses. All these components fit into place in the host cell cytoplasm in the form of fully functional virus particles. This is a very efficient process and readies the viruses for their next cycle of virus reproduction. From here onwards those viruses leave the host cell to infect other cells and continue the infection cycle.
The final step in the virus cycle of life is the release of the new virus particles. Lysis is when the host cell bursts open and releases a large number of viruses but kills it in the process.
This is where the viruses out from the host cell's membrane taking along a portion of it to be their envelope which excludes them from the reach of the immune system. This makes sure that the cycle of virus production continues because newly formed viruses move to other cells and repeat through the same cycle.
The diagram below represents the process of a virus life cycle.
The virus then latches onto human cells by binding to a protein called ACE2, thus beginning the life cycle of the virus.
It penetrates the human cells, hides from the immune system, and initiates virus replication.
Inside the cell, it captures that cell makes copies of its RNA and produces viral proteins for virus reproduction.
The virus, with its replicated RNA and proteins, puts together new particles.
It buds out of the cell taking part of the membrane of the cell in a coat in order not to be detected.
The newly produced viruses spread to infect other cells, perpetuating the life cycle of the virus and ensuring more virus reproduction.
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The viral life cycle defines the steps that a virus uses to infect a host cell to replicate the genomic material and form new virions.
These viruses replicate by taking the cellular machinery of the host cell for the synthesis of viral components: genetic material and proteins.
Basically, the steps in viral infection include attachment to host cells, penetration or entry into cells, replication of viral genome, assembly of new virions, and release of viruses from the host cell.
The lytic cycle replicates host cells immediately and lyses them to release new viruses, while in the lysogenic cycle, viral DNA integrates into the host genome to remain dormant until it ends up in the lytic cycle.
Viruses cause disease through the direct action of replication and host cell damage, the induction of immune responses, and, in some cases, the production of toxins that make a poisonous impact on cell function and health.
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