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Quick Facts
| Medium Of Instructions | Mode Of Learning | Mode Of Delivery |
|---|---|---|
| English | Self Study | Video and Text Based |
Course Overview
This Medicinal Chemistry: The Molecular Basis of Drug Discovery training is a seven weeks online course. This course is produced by a partnership between DavidsonX and the Novartis Institutes of BioMedical Research and delivered through the EDX platform. This course was explained by Erland Stevens who is a professor at Davidson College.
This medicinal chemistry course investigates how chemists modify the structure of a molecule to create a safe and effective drug. This course begins with a brief history of drug discovery and progresses to an overview of the modern drug approval process.
Then, users will learn about receptors and enzymes, the molecules in the body that are most commonly targeted by drugs. Users can also discuss pharmacokinetics (drug adsorption, elimination, and half-life) and metabolism in this forum. This course concludes with units on the identification of potential drug molecules and their subsequent optimization into safe and effective drugs.
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The Highlights
- Seven weeks online course
- 6-8 hours per week
- Self-paced
- Shareable completion certificate
- Video transcript
- Access to course materials
Programme Offerings
- Graded Assignments and Exams
- Intermediate level
- Davidson designed syllabus
- World-class institutions
- and universities
Courses and Certificate Fees
| Certificate Availability | Certificate Providing Authority |
|---|---|
| yes | Davidson College, Davidson |
Eligibility Criteria
Educational Qualifications
Chemistry and biology at the high school level, as well as some experience with organic chemistry and basic math skills are also recommended (logarithms and exponential functions).
Certification Qualifying Details
The completion of the Medicinal Chemistry: The Molecular Basis of Drug Discovery certification by DavidsonX and the Novartis Institutes of BioMedical Research, delivered via the EDX platform. Davidson College does not award academic credit for courses taken through edX.org. Only a passing grade in a DavidsonX course(s) will qualify for a verified certificate generated by edX.org.
What you will learn
After completing this Medicinal Chemistry: The Molecular Basis of Drug Discovery certification syllabus, users will understand how to measure enzyme and receptor activity, as well as methods for modeling a drug's half-life and predicting and modifying a molecule's metabolism. Techniques for identifying molecules with desired biological activity, as well as approaches for optimizing a molecule into a safe and effective drug.
Who it is for
Candidates who are interested in the medical field and who want to deal with effective drugs can apply for this online course.
Admission Details
Students may take the following steps to gain admission to Medicinal Chemistry: The Molecular Basis of Drug Discovery certification course classes:
Step 1: Follow the official URL: https://www.edx.org/course/medicinal-chemistry-the-molecular-basis-of-drug-di
Step 2: Participants must create an account on the Edx website.
Step 3: Only after the participant has registered and logged in is admission confirmed.
The Syllabus
- Early natural products and synthetic molecules used as drugs
- Safety issues in the first drugs
- Modern drug discovery and approval process
- Intellectual property issues with drugs
- Structure of proteins Enzymes, enzymatic activity, and inhibition
- Receptors and molecules that modulate their activity
- Examination 1
- Drug transport in the blood
- Clearance
- Volume of distribution
- Compartment modeling
- Types of metabolic reactions
- Genetic and population effects
- Prodrugs
- Examination 2
- Intermolecular forces
- Drug-target complementarity
- Molecular diversity and chemical libraries
- Combinatorial chemistry
- Drug screening
- Filtering hits to find leads
- Existing drugs and natural products as leads
- Functional group replacements
- Alkyl group replacements
- Isosteres and bioisosteres
- Peptidomimetics
- Examination 3
Instructors
Davidson College, Davidson Frequently Asked Questions (FAQ's)
An English video transcript is available for this online course.
This is a seven-week online course that requires a six-to-eight-hour weekly time commitment.
This is a self-paced course.
This course was created through a collaboration between DavidsonX and the Novartis Institutes of BioMedical Research and is delivered via the EDX platform.
Erland Stevens, a professor at Davidson College, explained this course.
Davidson College does not grant academic credit for edX.org courses. Only a passing grade in a DavidsonX course(s) qualifies for a verified certificate from edX.org.