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Quick Facts

Medium Of InstructionsMode Of LearningMode Of Delivery
EnglishSelf StudyVideo and Text Based

Course Overview

The Library of Integrative Network-based Cellular Signatures (LINCS) is an NIH Common Fund programme. The aim is to perturb various types of human cells with different types of perturbations, genetic manipulations, and more. The Big Data Science with the BD2K-LINCS Data Coordination and Integration Center provides you with extensive knowledge of the functionality of LINCS and its practical application. 

The Big Data Science with the BD2K-LINCS Data Coordination and Integration Center online course aims to familiarise students with molecular networks which are affected by these disturbances. The curriculum includes different variables of measurement, like mRNAs, proteins, metabolites, and cellular phenotypic changes. The BD2K-LINCS Data Coordination and Integration Center (DCIC) provides this data along with other publicly available relevant resources. 

The Big Data Science with the BD2K-LINCS Data Coordination and Integration Center online programme also includes computational methods such as gene-set enrichment analysis, data clustering, interactive supervised learning, and data visualization. Candidates can also work on crowdsourcing or citizen-science projects in this 100% online training.

The Highlights

  • Flexible deadlines
  • Tangible Career Benefits 
  • Self-paced learning
  • English subtitles for videos
  • Financial aid 
  • Chapter-based quizzes
  • Intermediate level course 
  • Certificate by Coursera 
  • Readings and Practice Exercises for each module

Programme Offerings

  • Pre-recorded Video Lectures
  • Flexible Deadlines
  • Practice Exercises
  • 100% online course
  • Transcripts of Pre-recorded Videos
  • Shareable Certificate From Coursera.

Courses and Certificate Fees

Fees InformationsCertificate AvailabilityCertificate Providing Authority
INR 2435yesCoursera

Big Data Science with the BD2K Lincs Data Coordination and Integration Center Fees Structure

Course NameFees in INR
Big Data Science with the BD2K Lincs Data Coordination and Integration Center
Rs. 2,435

Eligibility Criteria

To get a certification in Big Data Science with the BD2K-LINCS Data Coordination and Integration Center online course, candidates need to complete the course successfully. They need to finish the complete modules which include video lectures, readings, and practise exercises in an MCQ-based format available at the end of each module. 

Lastly, candidates have to purchase the certificate to receive access to all the course content and assignments. Additionally, they can also link the certificate with their CVs, LinkedIn profiles, and resumes. 

What you will learn

Knowledge of Big DataKnowledge of bioinformatics

After successful completion of the Big Data Science with the BD2K-LINCS Data Coordination and Integration Center online training course, candidates will have proficiency in the following:

  • Understand and apply metadata and ontologies to LINCS datasets and how to access data through an application programming interface
  • Be able to understand the important concepts of a Bioinformatics pipeline and Harmonisome
  • Ability to compare and evaluate bioinformatics pipelines
  •  Understand mathematical concepts behind data normalisation and data clustering
  • Create interactive web-based data visualization elements or figures and work on LINCS-related projects outside of the training course

Who it is for


Admission Details

Candidates who want to join the Big Data Science with the BD2K-LINCS Data Coordination and Integration Center certification course should follow these steps:

  • Log on to the official website of Coursera.
  • In the search bar at the top, enter the name of the course, “Big Data Science with the BD2K-LINCS Data Coordination and Integration Center.”
  • At the top of the webpage, you will see a “Join for Free” tab. Once you select the tab, a form will appear. 
  • Use the form to register yourself on Coursera or login via Facebook, Google, or Apple accounts. But if you already have an account on Coursera, use it to log in and apply for the training course.

Application Details

There is no separate application form to join the Big Data Science with the BD2K-LINCS Data Coordination and Integration Center course. Candidates can sign up on Coursera for free and access the course materials.  

The Syllabus

Videos
  • Layers of Cellular Regulation and Omics Technologies
  • The Connectivity Map
  • Geometrical View of the Connectivity Map Concept
  • LINCS Data and Signature Generation Centers
  • BD2K-LINCS Data Coordination and Integration Center
  • Induced Pluripotent Stem Cells (iPSCs)
  • Introduction to LINCS L1000 Data
  • L1000 Characteristic Direction Signature Search Engine (L1000CDS2) Demo
Readings
  • Syllabus
  • Grading and Logistics

Videos
  • Introduction to Metadata and Ontologies | Part 1
  • Introduction to Metadata and Ontologies | Part 2

Videos
  • Accessing and Serving Data through RESTful APIs | Part 1
  • Accessing and Serving Data through RESTful APIs | Part 21

Videos
  • Analyzing Big Data with Computational Pipelines

Videos
  • The Harmonizome Concept
  • Processing Datasets | Part 1
  • Processing Datasets | Part 2
  • Processing Datasets | Part 3

Videos
  • Data Normalization | Part 1
  • Data Normalization | Part 2

Videos
  • Data Clustering | Part 1 | Introduction
  • Data Clustering | Part 2 | Distance Functions
  • Data Clustering | Part 3 | Algorithms and Evaluation

Practice Exercise
  • Midterm Exam

Videos
  • Enrichment Analysis | Part 1
  • Enrichment Analysis | Part 2
  • Enrichr Demo

Videos
  • Introduction to Machine Learning | Part 1
  • Introduction to Machine Learning | Part 2 
  • Introduction to Machine Learning | Part 3

Videos
  • Benchmarking | Part 1
  • Benchmarking | Part 2

Videos
  • Interactive Data Visualization with E-Charts
  • Visualizing Data using Interactive Clustergrams Built with D3.js | Part 1
  • Visualizing Data using Interactive Clustergrams Built with D3.js | Part 2
  • Visualizing Data using Interactive Clustergrams Built with D3.js | Part 3

Videos
  • Microtasks and GEO2Enrichr Demo
  • L1000-2-P100 Megatask Challenge

Reading

BD2K-LINCS DCIC Crowdsourcing Portal

Quiz
  •  Final Exam

Evaluation process

There are two exams in Big Data Science with the BD2K-LINCS Data Coordination and Integration Center certification programme. The midterm examination has 45, and the final exam has 60 MCQs.

Instructors

ISMMS New York Frequently Asked Questions (FAQ's)

1: When will I have access to the course content?

Your access to lectures, quizzes, exams, and assignments of your Big Data Science with the BD2K-LINCS Data Coordination and Integration Center online course depends on the type of enrollment you select. Courses taken in audit mode will allow access to the learning material for free. But for graded assignments and the certification, purchase the experience.

2: What is the advantage of purchasing the certificate?

Purchasing a Certificate allows access to all course materials, which includes your graded assignments as well. Once you complete the Big Data Science with the BD2K-LINCS Data Coordination and Integration Center course, your Coursera accomplishments page will have the digital certificate.

3: Is financial aid available?

Coursera offers financial aid to financially weak candidates. To avail the assistance, you need to click on the Financial Aid link under the "Enrol" tab on the left of the webpage. You will have to fill in an application, and you will be notified upon approval.

4: What if I cannot finish on deadlines?

Coursera provides an option of completing the curriculum with flexible deadlines; hence you can finish them on your own time.

5: How long will it take to finish the programme?

It will approximately take 9 hours to complete the course.

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