Learn Bioinformatics From Scratch (Theory & Practical)

BY
Udemy

Mode

Online

Fees

₹ 499 3099

Quick Facts

particular details
Medium of instructions English
Mode of learning Self study
Mode of Delivery Video and Text Based

Course and certificate fees

Fees information
₹ 499  ₹3,099
certificate availability

Yes

certificate providing authority

Udemy

The syllabus

Module 1 Databases

  • Definition of Databases
  • Database Design
  • Knowledge Discovery
  • Biological Databases
  • Take Home Key Points
  • Practical -1: NCBI Nucleotide Database
  • Practical-2: Protein Databank (PDB)
  • Quiz 1
  • Assignment 1

Module 2 Sequence Alignment

  • What is Sequence Alignment?
  • Some Important Terms
  • Types of Sequence Alignment
  • What is Algorithms?
  • Dot Matrix Algorithm; How Does It Work?
  • Dot Matrix Algorithm; How to Interpret The Results?
  • Dot Matrix Algorithm; Identification of Repeat Sequences
  • Dot Matrix Algorithm; Advantages Vs Disadvantages
  • Practical-3: DotMatcher for Qualitative Comparison of Sequence
  • Assignment 2
  • Dynamic Programming Method: How Does It Work?
  • How to Transform Scoring Matrix to Alignment?
  • Dynamic Programming; Some Important Terms to Understand
  • Comparison Between DotMatrix and Dynamic Programming
  • Practical-4: Global Pairwise Sequence Alignment Using DNA Sequences
  • Practical-5: Pairwise Sequence Alignment Using Protein
  • Practical-6: Local Pairwise Sequence
  • Assignment 3
  • Introduction to Database Searching; BLAST
  • Type of Algorithms
  • How Does Word Algorithm Work? (Part-1)
  • How Does Word Algorithm Work? (Part-2)
  • A Important Term For Word Algorithm
  • Important Statistical Values to Evaluate the BLAST Results
  • Different Type of BLAST Associated with NCBI Databases
  • Practical -7: How to Use BLAST Program
  • Assignment 4
  • Optional: How to Use PSI-BLAST
  • Multiple Sequence Alignment; An Introduction
  • Algorithms for Multiple Sequence Alignment
  • Progressive Sequence Alignment Algorithm
  • Tools for Multiple Sequence Alignment
  • Practical -8: How to Use CLUSTAL-W
  • Practical -9: How to Use T-COFFEE
  • Assignment 5
  • Quiz 2

Section 3 : Genomic Bioinformatics

  • Introduction of Module 3
  • What is DNA?
  • Where Is Our DNA is Located?
  • What Is Role of DNA?
  • What Does Gene Have?
  • Algorithms for Gene Prediction-1
  • Algorithms for Gene Prediction-2
  • GC-Bias and Test Code; An Ab-initio Type of Algorithm
  • Introduction of Markov Model (Part-1)
  • Introduction of Markov Model (Part-2)
  • Machine Learning and Gene Prediction
  • Practical-10: Prediction of Prokaryotic Gene
  • Practical-10.1 Prediction of Prokaryotic Regulatory Elements
  • Practical-11 Prediction of Eukaryotic Gene
  • Assignment 6
  • Assignment 7
  • Quiz 3

Module 4 : Structural Bioinformatics

  • What is Protein? (Part-1)
  • What is Protein? (Part-2)
  • Some Important Points
  • Role of Amino Acids in 3D Structure
  • Peptide Bond; A link between Amino Acids
  • Secondary Structures of Proteins
  • Double Bond like Character in Peptide Bond & Ramachandran Plot
  • Forces Stabilizing The Protein Structure
  • Practical 13: Visualization of Protein Structure in Pymol (Part-1)
  • Why Protein Structure Prediction is So Important?
  • Protein Secondary Structure Prediction Algorithms (Part-1)
  • Protein Secondary Structure Prediction Algorithms (Part-2)
  • Practical-15: Prediction of Globular Protein Secondary Structure
  • Assignment 8
  • Algorithm for Secondary Structure Prediction of Transmembrane Proteins
  • Practical-16: Prediction of Transmembrane Helix Secondary Structure
  • Assignment 9
  • 3D Structure Prediction Algorithms
  • Homology Based Algorithm (Part-1)
  • Homology Based Algorithm (Part-2)
  • Homology Based Algorithm (Part-3)
  • Homology Based Algorithm (Part-4)
  • Model Validation & Draw back of Homology Based Algorithm
  • Practical-17: Prediction of 3D structure Using Homology Modeling (Mdeller)
  • Assignment 10
  • Threading Algorithm for 3D Structure Prediction
  • Practical-18: Prediction of 3D structure Using Threading Technique (I-TASSER)
  • Assignment 11
  • (Optional) Practical-18.1: Use of InterPro
  • (Optional) Practical 20: How to Perform Docking easily Using Vina
  • (Optional) Practical-21: How to Analyze the Docking Data
  • (Optional) Practical 3: ZINC Database for Drug Searching
  • Quiz 4
  • (Very Important) Practical Learn How to Use Alpha-Fold
  • Update Another GOR-IV Server for Secondary Structure Predictions

Module 4 : Evolutionary Bioinformatics

  • What is Evolution and Phylogenetics
  • Some Important Terms To Understand Phylogenetic Tree
  • Different Type of Phylogenetic Trees
  • Steps To Construct Phylogenetic Tree
  • Selection of Molecular Marker for Tree Construction
  • Alignment for Tree Construction
  • Evolutionary Model Selection
  • Methods To Construct Tree
  • Validation of Tree By Bootstrapping
  • Practical -19: Building Phylogenetic Tree
  • Assignment 12
  • Quiz 5

Module 6 (Optional)

  • Practical-22: How to Install Linux in Window for Bioinformatics Analysis
  • Practical-23: How to Install Gromacs in Windows
  • Practical-24: How to Download Chemsketch
  • Practical-25: Ligand Drawing and Making of Ligand 3D Structure

Instructors

Dr Muhammad Dujana

Dr Muhammad Dujana
Instructor
Freelancer

Ph.D

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