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Quick Facts

Medium Of InstructionsMode Of LearningMode Of Delivery
EnglishSelf StudyVideo and Text Based

Course Overview

The Advanced NMR Techniques in Solution and Solid-State certification by IISc Bangalore is a 12-week online course. This online certification course is designed for postgraduates and research students providing them with an introduction to NMR and the internal interaction parameters. The Advanced NMR Techniques in Solution and Solid-State certification syllabus at IISc Bangalore will also discuss some advanced concepts and techniques, such as NOE and ROE, spin system nomenclature, relaxation phenomenon and their measurements, quantum mechanical analysis of spectra, chemical exchange, and others.

The Advanced NMR Techniques in Solution and Solid-State online course is delivered online via Swayam. To pursue this online course, students are required to have a basic knowledge of NMR Spectroscopy and Analysis of Spectra. Upon completion of the Advanced NMR Techniques in Solution and Solid-State training programme, they can enter the pharma industries that have NMR facilities.

The Highlights

  • Offered by IISc Bangalore
  • 12 weeks online course
  • 3 credit points
  • In-person proctored exam
  • Certificate of completion

Important dates

Course Commencement Date

Start Date : 20 Jan, 2025

End Date : 11 Apr, 2025

Enrollment Date

End Date : 27 Jan, 2025

Other

End Date : 14 Feb, 2025

Certificate Exam Date

Start Date : 04 May, 2025

Programme Offerings

  • 12 weeks of learning content
  • Learner-centric curriculum
  • Expert Faculty
  • Free online course
  • Proctored-based offline examination
  • Certification.

Courses and Certificate Fees

Fees InformationsCertificate AvailabilityCertificate Providing Authority
INR 1000yesIISc Bangalore

There is no Advanced NMR Techniques in Solution and Solid-State certification fee. This online course is available for free. However, to get a verified certificate, students will have to appear in an in-person proctored exam conducted at designated exam centres. For this, they will be required to pay an examination fee of Rs 1,000.

Advanced NMR Techniques in Solution and Solid-State Fee Structure

Description

Amount

Exam Fee

Rs. 1000


Eligibility Criteria

Eligibility

Postgraduates and research students can enrol in the Advanced NMR Techniques in Solution and Solid-State training course offered by the Indian Institute of Science (IISc), Bangalore via Swayam.

Certification Qualifying Details

After completion of the Advanced NMR Techniques in Solution and Solid-State online course, students will be awarded a digital certificate having their name, photograph and final exam score with the logos of NPTEL and IISc Bangalore.

What you will learn

Knowledge of physics

By pursuing the Advanced NMR Techniques in Solution and Solid-State certification course, students will:

  • Learn NMR and the internal interaction parameters.
  • Understand the Pulse phase and Receive phase, Chemical shifts evolution, Scalar Couplings evolution, Relaxation Concept and Mechanisms.
  • Know about the advanced concepts and techniques such as diffusion ordered spectroscopy, spectra of many hetero nuclei, 2D NMR and routine 2D experiments.
  • Learn CPMAS techniques and solid-state NMR experiments 

Who it is for

Advanced NMR Techniques in Solution and Solid-State certification by IISc Bangalore is designed for students who have completed post-graduation and research fellows. The course is also apt for those seeking to explore careers as Physicists. 


Admission Details

Candidates willing to enrol in the Advanced NMR Techniques in Solution and Solid-State online course from IISc Bangalore via Swayam must check the following steps:

Step 1: Candidates’ Account Creation and Registration

Step 2: Filling up the Application Form

Step 3: Admission Confirmation

Application Details

Applicants may apply for the Advanced NMR Techniques in Solution and Solid-State certification course by following the below-mentioned instructions:

  • Visit the official website - https://onlinecourses.nptel.ac.in/noc25_ph02/preview
  • Create an account and register themselves
  • Complete the application form by providing the required details
  • Submit the form

The Syllabus

  • NMR spin physics
  • concepts
  • Chemical shifts

  • J couplings
  • Splitting patterns 
  • Analysis of 1H 1
  • 3C and the spectra of other heteronuclei

  • Fourier series, transformation
  • FT of different functions, 
  • Theorems of FT, 
  • Use of FT theorems in NMR, 
  • Pople nomenclature, 
  • Quantum mechanical analysis of spectra of two coupled spins

  • Wave functions, 
  • product functions of weakly coupled spin systems, 
  • othronormalization, 
  • Hamiltonian for uncoupled spins, 
  • coupled spins, 
  • eigen values and eigen functions, 
  • strongly coupled spin systems. 
  • RF pulse, 
  • pulse phase, 
  • precession of magnetization under 90, 
  • 180 and 360 pulses and their phases, 
  • absorption and dispersive signals, 
  • FT of cosine and sine functions, 
  • phase cycling

  • Polarization transfer, 
  • SPT and SPI for homo and heteronuclear spin systems, 
  • INEPT sequence, 
  • coupled and decoupled INEPT, 
  • DEPT sequences, 
  • coherence transfer pathways, 
  • selection of particular pathway in different sequences, 
  • phase cycling

  • Phases of pulses and receivers, 
  • multiple pulse sequences, 
  • PFGs, and selection of coherence transfer pathways using gradients, 
  • in homo and heteronuclear cases, 
  • use of gradients for removal of pulse artifacts, 
  • purge pulse, etc. 
  • selective inversion, 
  • relaxation concepts

  • T1 relaxation phenomenon and its deeper concepts, 
  • correlation times, 
  • relaxation processes, 
  • measurement of T1, 
  • T¬2 relaxation, 
  • spin echo experiment

  • Decoupling and NOE, 
  • concepts and the factors governing NOE. 
  • Product operators, 
  • concept of product operators, 
  • product operators in understanding rotations. 
  • Hamiltonians and evolution of couplings, 
  • chemical shifts Hamiltonians and free precession

  • Product Operator analysis of one pulse experiment, 
  • spin echoes in coupled and uncoupled spins, 
  • operators for two coupled spins, 
  • free precession Hamiltonian for two coupled spins, 
  • evolution of inphase and antiphase terms, 
  • heteronuclear spin echoes, 
  • coherence transfer, 
  • INEPT using product operators

  • Concepts of different 2D experiments, 
  • general interpretation of 2D experiments, 
  • discussion on the COSY, 
  • limitations of COSY experiment, 
  • different COSY sequences, 
  • DQF COSY, 
  • TOCSY, 
  • coupled and decoupled HSQC, 
  • HMBC, 
  • INADEQUATE

  • Multiple Quantum NMR, 
  • DQ and SQ transitions, 
  • and their detection. 
  • Higher quantum spectra in coupled spin systems, 
  • spin system filtering, 
  • spin state selection, 
  • measurement of relative signs of the couplings, 
  • Introduction to NMR spectra of solids

  • Solid state NMR, 
  • MAS, 
  • spin space averaging, 
  • decoupling in solids, 
  • cross polarization, 
  • CRAMPS, 
  • side bands, 
  • VSMAS, 
  • CP at high speeds

Evaluation process

Students are required to sit for an examination for the Advanced NMR Techniques in Solution and Solid-State training course to get a certificate.

The exam will be conducted in person at the designated exam centres. There are 25% marks are allotted for the best eight assignments out of the total 12 assignments given in the course where students need to secure at least 10 marks. Conversely, 75% of marks are allotted for the proctored certification exam which is conducted for 100 marks where students are required to score at least 30%. So, a student has to secure>= 40/100 to earn the certificate.

Instructors

IISc Bangalore Frequently Asked Questions (FAQ's)

1: What is the course duration?

Advanced NMR Techniques in Solution and Solid-State is a 12-week online certificate course.

2: Does the course provide any credit points?

Yes, the course has four credit points which will be given to the students after completion.

3: When can I fill up the registration form?

The announcements will be made by the institute when the registration form is open for registrations.

4: Will I get the hard copy of the certificate?

No, the certificate will be made available in digital format.

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