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Quick Facts

Medium Of InstructionsMode Of LearningMode Of Delivery
EnglishSelf StudyVideo and Text Based

Course Overview

The Essentials of Oxidation, Reduction, and C-C Bond Formation by IIT Bombay and IISER Thiruvananthapuram, emphasizes concepts like selectivity, mechanism, stereochemistry, and their applications in synthetic problems. This postgraduate course falls under the domain of chemistry. Candidates registering for this course can also obtain a highly valuable accreditation from NPTEL and IIT Bombay.  

The Essentials of Oxidation, Reduction, and C-C Bond Formation certification is also an FDP course approved by AICTE. Spread over twelve weeks, the program is taught by Dr. Padma Shree Vankar, who has a Ph.D. in Chemistry from IIT Kanpur. Her specialization is synthetic organic chemistry, and she has several years of expertise under her name. 

The Essentials of Oxidation, Reduction, and C-C Bond Formation certification syllabus outlines all the essential concepts related to C-C bond formation. The course contents include all the topics like selectivity, swern oxidation, IBX, microbial oxidations, Sharpless epoxidation, Simmons-Smith cyclopropanation, Tamao fleming oxidation, and photosensitized oxidations.

The Highlights

  • Course offered by IIT Bombay and IISER 
  • Extensive coverage of syllabus
  • Course taught in English 
  • In-course assignments
  • Certificate offered
  • End-term proctored exam
  • Twelve-week course
  • E-certificate only
  • Postgraduate course 
  • Falls under the domain of chemistry

Programme Offerings

  • Falls under the domain of chemistry
  • Course offered by IIT Bombay and IISER
  • Postgraduate course
  • Course taught in English
  • E-certificate only
  • In-course assignments
  • Twelve-week course
  • End-term proctored exam
  • Certificate offered
  • Extensive coverage of

Courses and Certificate Fees

Fees InformationsCertificate AvailabilityCertificate Providing Authority
INR 1000yesIIT Bombay

The Essentials of Oxidation, Reduction, and C-C Bond Formation fees for enrolling and learning are zero. However, if the candidate is interested in obtaining a certificate, then he/she is required to pay a fee of Rs 1,000. 

Essentials of Oxidation, Reduction, and C-C Bond Formation fee structure 

Course name

Fees

Essentials of Oxidation, Reduction, and C-C Bond Formation

Rs 1,000


Eligibility Criteria

The Essentials of Oxidation, Reduction, and C-C Bond Formation training mandates students to have a background of B.Sc course with a specialization in chemistry. Specialization in organic chemistry courses is preferred as it enhances the scope of understanding of the course. 

Students who are willing to obtain the Essentials of Oxidation, Reduction, and C-C Bond Formation certification, must appear for an end-term proctored examination. The candidates will be eligible to receive certification only if their average assignment score is greater than or equal to 10/25 and the proctored exam score is greater than or equal to 30/75. 

Even if the registered students obtain a final score greater than or equal to 40/10, they will not receive a certificate in case any one of the above conditions is not met.

What you will learn

Knowledge of Chemistry

Upon completing the Essentials of Oxidation, Reduction, and C-C Bond Formation certification course, candidates can be assured of gaining knowledge in the following areas:-

  • Reduction with silanes
  • Dissolving metal reactions
  • Corey’s oxazaborolidine in asymmetric reduction
  • Noyori’s ruthenium in asymmetric reductions 
  • Asymmetric hydrogenations with BINAP
  • C-C bond formation through carbanions alpha to electron-withdrawing groups

Who it is for

The Essentials of Oxidation, Reduction, and C-C Bond Formation online course is perfect for students pursuing an M.Sc degree in chemistry.


Admission Details

  • To visit the Essentials of Oxidation, Reduction, and C-C Bond Formation course page, you can click on the undermentioned link here:  https://onlinecourses.nptel.ac.in/noc22_cy27/preview
  • Once the page opens, you will find the ‘Sign-in/Register’ button on the top.
  • From the web page that appears after clicking on it, you can fill in your login credentials to sign in to the portal. If you already have an account with Swayam, you could use those details to log in. 
  • Once you log in, you will be directed to a page where you need to fill in your personal and educational details. 
  • Complete filling the form and proceed to the course portal where you can access all the course contents. 

Application Details

The Essentials of Oxidation, Reduction, and C-C Bond Formation certification course does not require the students to fill any other application forms except for the basic details of name, email address, contact details, the highest level of education, etc. 

The Syllabus

  • Lecture 1 
  • Introduction to organic synthesis, importance of selectivity and basics of oxidation of alcohols and development of sulfur based oxidations: Swern oxidation and related concepts 
  •  Lecture 2
  • Continuation of Swern oxidation and the utility of intermediates derived from Swern oxidation including Pummerer intermediates
  •  Lecture 3   
  • Oxidations using selenium compounds such as SeO2 and organoselenium compounds

  • Lectures 4 and 5 
  • Dess-Martin
  • IBX and related hypervalent iodine based oxidations
  • Lecture 6
  • Silver carbonate/celite
  • Prevost reactions and its modern variation
  • Microbial oxidations such as Pseudomonas Putida etc 

  •  Lecture 7 
  • Oxidations with RuO4 and other Transition metal catalysed oxidations 
  •  Lecture 8
  • Tamao-Fleming Oxidation 
  • Lecture 9
  • Oxidations with Dimethyl dioxirane (DMDO) and 2-sulfonyloxaziridines and chiral versions 
  •  Lecture 10
  • Oxidations at unfunctionalised carbons
  • Photosensitized oxidations

  • Lectures 11-14 
  • Reduction of Carbonyl compounds with Boron and Aluminium based reagents such as Luche Reduction, NaCN(BH3), DIBAL, Red-Al, L-and K-Selectrides, Superhydrides and associated selectivities.

  • Lecture 15 
  • Low Valent Titanium species and Microbial reductions (NADH model etc.) 
  •  Lecture 16 
  • Dissolving Metal Reductions 
  • Lecture 17 
  • Reduction with Silanes

  • Lectures 18 and 19 
  • Sharpless epoxidation and synthetic utility of the chiral epoxy alcohols 
  • Lecture 20 
  • Katsuki-Jacobsen epoxidation and mechanistic details 
  • Lectures 21 
  • OsO4 based and related Sharpless Asymmetric Dihydroxylation

  • Lecture 22 
  • Corey’s oxazaborilidines in asymmetric reductions 
  • Lecture 23 
  • Noyori’s Ruthenium catalysed reduction of ketones 
  • Lecture 24 
  • Asymmetric Hydrogenations with BINAP

  • Lecture 25 
  • C-C Bond formation via Carbanions alpha to electron withdrawing groups 
  • Lecture 26 
  • Boron and Silicon Enolates: Formation and Use in C-C Bond Formation 
  • Lecture 27 
  • Imines in C-C Bond Formation 
  • Lecture 28 
  • Simmons-Smith Cyclopropanation in Organic Synthesis

  • Lectures 29-32 
  • Use of Allyl Boron, Allyl and Vinyl Silanes and Allyl Tin compounds in C-C Bond Formation

  • Lecture 33 
  • Introduction to SAMP and RAMP chiral ligands for asymmetric C-C bond formation 
  • Lecture 34 
  • Introduction to Oppolzer’s Sultam based chiral ligands and their reactions for organic synthesis 
  • Lectures 35 and 36 
  • Evans’ Oxazolidinone for asymmetric synthesis

  • Lectures 37 and 38 
  • Synthesis of selected natural products using above discussed methods of oxidation
  • Reduction and C-C Bond formations

  • Lectures 39 and 40 
  • Synthesis of selected natural products using above discussed methods of oxidation
  • Reduction and C-C Bond formations

Evaluation process

Candidates interested in receiving the accreditation must appear for an end term proctored exam. The date of the examination is available on the website and the students must register for the exam through a URL sent by the course organizers. 

Moreover, the average assignment score of 25% (average of the best 8 assignments submitted out of a total of 12 assignments) will be considered. The end term exam on the other hand contributes towards 75% of the final score. The students must get an average assignment score of >= 10/25. Similarly, an average score >= 30/75 needs to be obtained in the end-term proctored exam. 

Even if any one of the above conditions is not satisfied, the candidate will not be eligible for a certificate despite the candidate securing a final score >= 40/100.

Instructors

IIT Bombay Frequently Asked Questions (FAQ's)

1: Will I get a hard copy of the certificate?

No, you will only receive an e-certificate. 

2: Are there any prerequisites to enroll for the course?

Yes. Students with a background of B.Sc in chemistry are preferred.

3: Is the course duration long?

Yes, however, you can quickly complete the course with a decent effort in 12 weeks. 

4: Does the course curriculum match the industry standards?

Yes. The curriculum updated as per the dynamic industry standards regularly.  

5: Where will the exam be conducted?

The examination will be held at the designated exam centers.

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