Case Studies in Personalized Medicine is an online certification course designed to help you understand how genetics is being used to refine diagnoses and personalise treatment. Biomedical advances are changing the way we treat diseases. The Case Studies in Personalized Medicine certification by Coursera will give you an overview of how genetics affects how our bodies respond to drugs, and how genetics is being used to personalise treatment for rare and common diseases. The course also discusses the ethical and operational challenges of large-scale genomic sequencing.
The Case Studies in Personalized Medicine certification consists of six modules with a total duration of 18 hours, giving you insight into the fundamentals of genetics, such as how genes work and how they are inherited. It will also explain how our genes can affect how our bodies respond to drugs, and how genetics is being used to improve the accuracy of diagnoses and to personalise treatment for individual patients. Additionally, the course will explore the ethical and operational challenges of large-scale genomic sequencing.
The Highlights
3 week course
Vanderbilt University
Subtitles in 5 languages
18 hours of learning
Programme Offerings
Certificate of completion
Online Classes
assessments
flexible schedule
Case Studies
Courses and Certificate Fees
Fees Informations
Certificate Availability
Certificate Providing Authority
INR 2435
yes
Coursera
If you opt for the certificate, the fee for the Case Studies in Personalized Medicine Certification is Rs. 2435/-. However, you can audit the course without the certificate for free.
Case Studies in Personalized Medicine Certification Fee Structure
Particulars
Total Fee
Course with Certificate
Rs. 2435/-
Course without Certificate
Free
Eligibility Criteria
Certification Qualifying Details
The Case Studies in Personalized Medicine certification by Coursera is offered to the ones who complete all six modules of this course successfully.
What you will learn
After completing the Case Studies in Personalized Medicine certification syllabus, you will have a better understanding of how genetic variants can contribute to human disease susceptibility. You will also learn about the ethical and operational challenges of large-scale genomic sequencing.
Upon completion of the Case Studies in Personalized Medicine training, you will learn how to choose among drug therapies based on genetic factors and understand that the functional consequences of the vast majority of genetic variants discovered by modern sequencing are still unknown.
The Case Studies in Personalized Medicine certification is primarily designed for physicians who are more than five years out of training. This course can also be pursued by healthcare professionals such as:
General Physicians
Doctors
Biotechnologists
Bioinformatics Scientists
Geneticists
Admission Details
Candidates can check out the step-by-step process to join the Case Studies in Personalized Medicine classes:
Step 1: Browse the official URL: https://www.coursera.org/learn/personalizedmed
Step 2: Click the ‘Enroll’ button.
Step 3: Sign up or log in with your credentials.
Step 4: You will be directed to the payment gateway, there you can pay the course fee and access the modules.
Application Details
In order to enrol in the Case Studies in Personalized Medicine online course, students must sign up or log in on the official provider website.
The Syllabus
Videos
A welcome message from Dr. Roden
Introduction to Personalized Medicine
Genetics Definitions, Part I
Genetics Definitions, Part II & Types of Genetic Variants
Data Analysis, Part I: What is a Good Study?
Data Analysis, Part II: What is a Good Test?
Introduction to Drug Therapy and General Mechanisms Underlying Variability in Drug Responses
Variability in Drug Therapy
Drug Metabolism & Transport
Genetic Variability in Drug-Handling Molecules
**Inside VUMC: The Promise of Personalized Medicine
Reading
About this course
Practice Exercise
Introduction to Personalized Medicine
Discussion Prompt
What kinds of data are helpful?
What is a good study?
What is a good test?
Why might an individual who has a non-sense variant not have a phenotype?
What are causes of variability in drug action?
Videos
Family History and Inheritance Patterns
Ancestry: Genetic Variation Across Generations and Geography
Finding Disease-Associated Genes: Linkage
**Inside VUMC: From Phenotype to Genotype and Back: Studying Heart Disease in Families
Genome-Wide Association
Sequencing
**Inside VUMC: History of Sequencing Technologies
Practice Exercise
Studying Genetic Variation
Discussion Prompt
What are causes of incomplete penetrance?
How big should your GWAS sample size be?
How big would the odds ratio need to be?
Can sequencing inform understanding of common diseases?
Videos
From rare to common disease: familial hypercholesterolemia
Using Genomics to Find New Drug Targets: Familial Hypercholesterolemia
Muscle Pains During Statin Therapy (Myopathy)
HLA-Mediated Immune Reactions (Skin Rash)
Long QT Syndromes, Part 1
Long QT Syndromes, Part 2
**Inside VUMC: Studying Cardiac Arrhythmias in Cells
A Second Heart Attack a Month After a First
Headache During Venlafaxine (Antidepressant)
Respiratory Arrest After Tonsillectomy
A Bleeding Complication 5 Days After Starting Warfarin
**Inside VUMC: Genotyping
Drug Metabolism and Variable Drug Responses – Four More Examples
Practice Exercise
Case Studies, Part I
Discussion Prompt
PCSK9 mutations and familial hypercholesterolemia
Simvastatin-related myopathy
Which drug-gene interactions warrant testing?
Should RCTs be done on every pharmacogenomic association before clinical implementation?
Videos
Cystic Fibrosis
Marfan Syndrome
A Case of Idiopathic Heart Failure
Personalizing Care in Neuropsychiatric Disease
Personalizing Care in Diabetes
Genomics to Subtype Cancer
A Family Member With Breast Cancer
A Family Member With Colon Cancer
**Inside VUMC: Organizing Infrastructure to Support Genetic Testing Decisions
Practice Exercise
Case Studies, Part II
Discussion Prompt
How much should a drug cost?
What data are needed in decisions about starting lithium therapy?
Would you order a CYP2D6 genotype before starting venlafaxine?
When to test for BRCA1 mutations?
Videos
Where We Are Now
Where We Are Going
**Inside VUMC: Using iPSCs: Drug Discovery and Drug Efficacy
**Inside VUMC: Generating iPSCs
Electronic Medical Records & The Learning Healthcare System (Discovery)
Using Electronic Records to Personalize Care (Delivery)
**Inside VUMC: Using the EMR to Ascertain Patients for Genetic Studies
**Inside VUMC: Biobanking & DNA Extraction at BioVU
**Inside VUMC: Personalized Medicine is a Team Sport
Practice Exercise
Personalized Medicine in a System of Care
Discussion Prompt
What limits our use of genomic sequencing data in practice?
What are possible drawbacks to widespread use of EMRs?
What are the barriers to widespread implementation of genomic medicine?
Instructors
Vanderbilt Frequently Asked Questions (FAQ's)
1: Can I access the Case Studies in Personalized Medicine online course materials for free?
Yes, you can access the course materials for free by auditing the course. However, the certification is available only when you buy the course.
2: Who is providing the Case Studies in Personalized Medicine certification course?
This online course is offered by Vanderbilt University and provided by Coursera.
3: Who can apply for the Case Studies in Personalized Medicine online course?
Anyone interested in learning more about the role of genetics in human health can apply for this course.
4: Who is the instructor of the Case Studies in Personalized Medicine certification?
This course is taught by Professor Dan Roden from Vanderbilt University.
5: This course is taught by Professor Dan Roden from Vanderbilt University.
This online course consists of six modules, spanning approximately 18 hours.