Chemical coordination or integration involves the regulation and control of some body functions by hormones, which are chemical messengers. This process helps in maintaining homeostasis, growth, and metabolism in a living organism. This chapter of Biology is important for the students appearing for Class 11 as well as the competitive entrance exams such as NEET, AIIMS, and paramedical. The article covers everything you need to know about chemical coordination and integration, from its definitions to different types of hormones and their importance in various exams.
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Chemical coordination and integration is the process of controlling all the physiological activities of the organism by hormones. Hormones are chemical substances that are produced in the body by endocrine glands and transported through the blood to target organs where they have specific effects. This system functions together with the nervous system to ensure that various body processes like growth and reproduction along with metabolism take place effectively.
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Peptide hormones are another important class of hormones that participate in chemical coordination and integration. These are amino acid derivatives secreted from several endocrine glands. Some examples are:
Insulin: regulation of blood sugar
Glucagon: increases in blood sugar
Parathyroid: hormone-regulation of calcium concentration in blood
These are soluble in water and work as agonists, binding to receptors on target cell surfaces, which starts their action inside the cell.
Some key concepts associated with chemical coordination and integration are:
This system consists of glands that secrete hormones directly into the blood.
The major glands include the pituitary, thyroid, adrenal, pancreas, and gonads (the ovaries and testes).
Hormones are messengers that can manage a wide range of physiological processes, including metabolism, growth, and reproduction.
For example, thyroxine in the thyroid controls metabolic rate whereas cortisol in the adrenal glands manages an organism's reaction to stress.
Hormonal regulation follows a feedback loop, frequently negative feedback, in which the product of a system represses or augments its own activity.
For example, the regulation of blood sugar by insulin and glucagon.
The table given below shows the major hormones, glands and their functions:
Hormone | Source Gland | Target Organ/Cells | Main Function |
Insulin | Pancreas (Beta cells) | Liver, Muscle, Fat Cells | Lowers blood glucose levels by facilitating glucose uptake in cells |
Glucagon | Pancreas (Alpha cells | Liver | Increases blood glucose levels by promoting glycogen breakdown |
Thyroxine (T₄) | Most Body Cells | Regulates metabolism, heart rate, and body temperature | |
Cortisol | Liver, Immune System, Muscles | Manages stress response, increases blood sugar, suppresses immune function | |
Adrenaline (Epinephrine) | Heart, Lungs, Muscles | Increases heart rate, blood flow to muscles, and energy during a "fight or flight" response | |
Growth Hormone (GH) | Pituitary Gland (Anterior) | Bones, Muscles | Stimulates growth, cell reproduction, and regeneration |
Parathyroid Hormone (PTH) | Bones, Kidneys | Regulates calcium levels by increasing blood calcium and promoting calcium reabsorption | |
Oxytocin | Pituitary Gland (Posterior) | Uterus, Mammary Glands | Stimulates uterine contractions during childbirth and milk ejection during breastfeeding |
Aldosterone | Regulates sodium and potassium balance, controls blood pressure | ||
Testosterone | Testes | Stimulates sperm production, secondary sexual characteristics | |
Estrogen | Ovaries | Regulates menstrual cycle, secondary sexual characteristics | |
Progesterone | Ovaries | Uterus | Prepares the uterus for pregnancy, supports embryo implantation |
In NEET, this chapter usually goes into MCQs that involve the functions of hormones and the function of various endocrine glands. Some of the common NEET PYQs pertaining to chemical coordination and integration are as follows:
What is the source and function of insulin?
What is the role of the hypothalamus, and which part plays a vital role in regulating the endocrine system?
Hormonal disorders like diabetes and goiter
This is one of the Class 11 Biology syllabus chapters that set the base for human physiology. The important topics of chemical coordination and integration class 11 include:
The anatomy and physiology of the endocrine system.
Types of hormones(peptide, steroid, amine hormones).
Mechanism of regulation of hormones and feedback loops
It is essential to practice the NEET PYQ questions from previous years to crack the NEET exam. Some of the examples of chemical coordination and integration PYQ NEET questions are
Functions of peptide hormones.
Mechanism of action of steroid hormones.
What is Chemical Coordination with Example?
Below are some tips and tricks to prepare for the chemical coordination and integration chapter:
Mnemonics
Study Aids
Draw diagrams of the endocrine system to learn where the different glands are and what some of their diverse functions are.
Prepare a table listing the major hormones, their source glands, and their functions.
Multimedia
Flashcards
The table given below indicates the weightage and types of questions asked from chapter chemical coordination and integration in different exams:
Exam Type | Types of Questions | Weightage of Chemical Coordination and Integration |
Definitions, short answers on endocrine glands, hormones, and their functions | 6-8% | |
MCQs on hormone functions, endocrine system disorders, and feedback mechanisms | 5-7% | |
True/False on hormonal functions, scenario-based questions on hormonal regulation and endocrine health | 3-5% | |
Paramedical Exams | Case studies on hormonal imbalances, applications of hormone therapy, and effects of endocrine disorders | 2-4% |
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Yes, chemical coordination and integration are important for NEET. Questions from this chapter from Class 11 Biology are very frequently found in the NEET questions and form the important concepts to understand human physiology. MCQs on functions of different hormones, endocrine glands and mechanisms of Hormonal regulation form a significant part of competitive exams like NEET and AIIMS.
Insulin helps in the intake of glucose by cells so the content of blood sugar reduces.
The pituitary gland secretes the growth hormone that causes growth and cell reproduction.
Parathyroid hormone regulates the concentration of calcium in the blood, in case the concentration becomes low in the blood, the parathyroid gland releases parathyroid hormone which increases the absorption of calcium from the bones and by the kidneys.
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