Epithelial tissues involve layers of cells that cover the surfaces of the body both inside and out and form protective barriers with roles in absorption, secretion, and excretion. These tissues form tightly packed and continuous sheets to ensure that they work effectively as a selective barrier, controlling the exchanges of substances. Epithelial tissues also feature specialized structures like cilia and microvilli that enable their functional capabilities to extend to specific organs and systems.
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Epithelial tissues are classified based on the number of cell layers and the shape of the cells in the top layer.
Simple epithelium is a single layer of cells, which can be squamous, cuboidal, or columnar.
Structure and function: Cubeshaped cells
Functions in secretion and absorption
Locations:
Kidney tubules
Glandular ducts
Thyroid gland
Structure and function: Tall, column-like cells; specialized for absorption and secretion
Locations: the lining of the digestive tract; uterine tubes
Specialised forms: ciliated columnar epithelium as in the uterine tubes and the respiratory tract
Stratified epithelium possesses more than one layer of cells, making it well-suited for serving as a protective barrier. Considerable wear and tear takes place on the body surface—the skin, in particular.
Protective function
Locations: Ducts of sweat glands
Mammary glands
Structure and function: Multiple layers with columnar cells at the surface
Provides protection and secretion
Locations:
Male urethra
Large ducts of some glands
Pseudostratified epithelium appears to have multiple layers due to the varying positions of nuclei but all cells are attached to the basement membrane.
Single layer with varying cell heights
Functions in secretion and movement of mucus
Locations:
Respiratory tract
Transitional epithelium can stretch and change shape, accommodating fluctuation in the volume of the liquid in an organ.
Several layers of cells with varying shapes
Stretches to permit distension of the urinary organs
Urinary bladder
Ureters
Epithelial tissues have distinct features like cellularity, polarity, a basement membrane, and a high regenerative capacity.
Tight junctions: Create a seal between adjacent cells
Apical and basal surfaces: Apical (exposed) and basal (attached to basement membrane) sides
Thin, fibrous layer anchoring epithelium to underlying tissues
Provides support and regulates nutrient diffusion
Regenerative Capacity
Cell turnover and repair mechanisms:
The high mitotic rate for repair and renewal
Epithelial tissues perform various essential functions in the body.
Examples:
Skin epithelium
Mucosal linings of the mouth and digestive tract
Examples: Intestinal epithelium, which absorbs nutrients
Examples: Glandular epithelium that secretes hormones, enzymes
Examples: Kidney tubules that excrete waste products
Protection, absorption, secretion, and excretion.
The simple epithelium contains a single layer of cells. Stratified epithelium has multiple layers.
Located commonly in the respiratory tract.
Examples include cancer (carcinoma), infections, and autoimmune diseases, such as pemphigus vulgaris.
Epithelial tissue can be investigated using histological staining methods and several kinds of microscopy, such as light and electron microscopy.
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