Human health and disease focus on the physical, mental, and social well-being of people. It studies diseases, their causes, and how to prevent or treat them. It also explains how the immune system works and how disorders, infections, and lifestyles affect health. Learning about human health and disease is an important part of biology, as it helps improve the quality of life. The chapter carries a weightage of 5-6% of the total marks in NEET and 3-4% of the weightage of other entrance exams like Paramedical and Nursing.
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The "Human Health and Disease" chapter of Class 12 CBSE deals with the concept of health, its importance, and the numerous factors affecting it. The chapter further provides a series of causes of disease and various diseases, including infectious and non-infectious diseases, along with prevention and control. It further explains the immune system with accounts for innate and acquired immunity as well as vaccines. It covers such common human diseases as malaria, cancer, and AIDS, among others, and lifestyle diseases. At the same time, it focuses on good health through balanced diet, hygiene, and exercise.
Health can be defined as a state of well-being where an individual feels body, mind, and social well-being. It is not only the absence of disease but also having the energy and ability to enjoy life to the fullest. Good health is dependent upon healthy nutrition, staying active, getting ample rest, and managing stress. It also has to do with living in a clean environment and avoiding bad habits.
Many factors affect our health:
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A disease is a condition that causes the body or mind to perform abnormally. It results from some form of abnormality in the body, such as an infection, injury, or imbalance. Diseases can be caused by microbes, such as bacteria or viruses, unhealthy habits, or genes passed from parents. Some diseases are short-lived, such as the flu, and others, such as diabetes, last longer. Treatment and prevention also vary according to the disease.
Human diseases fall into two categories:
Congenital: A condition that has existed since birth
Acquired: Disease that occurs during a person's lifetime
Basic points about Congenital and Acquired are discussed below:
Congenital | Acquired |
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Pathogens are often responsible for the disease. Lifestyle choices, genetic factors and environmental factors are other causes.
Pathogens: Bacteria, viruses, parasites and fungi cause infectious diseases. For example, flu virus and tuberculosis.
Lifestyle Choices: smoking, poor diet, and lack of exercise and sleep can result in heart disease, diabetes, and obesity.
Genetic Factors: Genetic mutations are inherited and can lead to diseases such as cystic fibrosis or sickle cell anaemia.
Environmental Factors: Pollution, exposure to hazardous chemicals, and poor living conditions can lead to respiratory diseases, cancers, and other health issues.
Direct Contact: Diseases can be transmitted through direct contact. (For example, flu and chickenpox)
Indirect Contact: Diseases are transmitted via contaminated surfaces, objects, or food and water (norovirus or hepatitis A).
Vectors: Insects or animals act as a medium of transmission for diseases. They carry pathogens from one host to another. For example, mosquitoes transmit dengue and malaria fever.
Transmission via Air: Pathogens present in droplets spread through the air. For example, tuberculosis and COVID-19.
There is a famous saying, “Prevention is better than cure." There is a lot to do to protect yourself from disease.
Healthy Lifestyle: Have a balanced diet, sufficient sleep, and do some physical activities regularly to boost your immune system.
Hygiene: There is some minute work to do to reduce the risk of infections. Maintain cleanliness and proper sanitation. Wash your hands regularly before having a meal.
Vaccination: Immunise yourself against diseases like polio, influenza and measles by taking a vaccine and building immunity.
Eliminate risk factors: avoid exposure to harmful substances such as smoking, and alcohol.
Masks: Use masks to avoid pollution and air-borne diseases.
To treat bacterial, viral, and fungal infections, antibiotics, antivirals, and antifungals are used, respectively. Anti-inflammatory medications and painkillers are used to treat symptoms.
The table below lists the common diseases that affect humans:
Disease | Symptoms | Causes | Preventive Measures |
Malaria | Fever, chills, sweating, headache, nausea | Plasmodium parasite transmitted by Anopheles mosquitoes | Use insect repellent, mosquito nets, and antimalarial drugs |
Weak immune system, opportunistic infections, weight loss, fatigue | Human Immunodeficiency Virus (HIV) | Safe sex practices, avoid sharing needles, antiretroviral therapy (ART) | |
Tuberculosis (TB) | Persistent cough, chest pain, night sweats, weight loss | Mycobacterium tuberculosis bacteria | BCG vaccination, good ventilation, proper treatment of active TB cases |
Variations by type can include lumps, abnormal bleeding, weight loss, and fatigue | Genetic mutations, lifestyle factors (smoking, diet), environmental exposures | Regular screenings, healthy lifestyle, avoiding carcinogens | |
Diabetes | Increased thirst, frequent urination, fatigue, and blurred vision | Insufficient insulin production (Type 1) or insulin resistance (Type 2) | Healthy diet, regular exercise, maintaining a healthy weight, and monitoring blood sugar levels |
The immune system refers to the body's ability to fight off infections by invading viruses or foreign bodies. There are two types, such as.
Innate Immunity
This protection is available from the time of birth and provides barriers to attack by any foreign agent that causes infections. In addition, there are four types:
Acquired immunity
This type of resistance is directly related to the pathogen, and a person acquires it during his or her lifetime.
Allergies occur when the immune system reacts to certain things such as pollen, medicines, food, etc. The human immune system can distinguish between foreign molecules and bodies. However, there are cases when the body beats its cells. As a result, it is harmful to the body and is called an autoimmune disease. A usual example of such a given effect is rheumatoid arthritis.
Cancer refers to the uncontrolled and abnormal replication of cells. These cells capture and kill neighbouring tissues, and the continuous proliferation of cancer cells causes metastasis. The basics of cancer are discussed below:
Tumor Type | Description | Characteristics | Causes of Cancer |
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Drug abuse commonly includes cannabinoids, coca alkaloids and opioids. Few medicines can be found in the fungus, especially in flowering plants. Opioid drugs also bind to the opioid receptors present in the human GI tract and the CNS (Central Nervous System). On the other hand, cannabinoids interact with cannabinoid receptors in the brain. Examples of such drugs are hashish, marijuana, and charm.
Given below are some human health and disease NEET questions:
Which of the following is an example of an autoimmune disease?
a) Malaria
b) Diabetes mellitus
c) Rheumatoid arthritis
d) Tuberculosis
Ans: c) Rheumatoid arthritis
What is the primary cause of AIDS?
a) Bacteria
b) HIV virus
c) Plasmodium
d) Influenza virus
Ans: b) HIV virus
Which cells are responsible for antibody production in the immune system?
a) T-cells
b) B-cells
c) Neutrophils
d) Monocytes
Ans: b) B-cells
The vaccine for tuberculosis is:
a) DPT
b) BCG
c) Polio vaccine
d) Hepatitis vaccine
Ans: b) BCG
Which type of immunity is obtained through vaccination?
a) Natural active immunity
b) Artificial active immunity
c) Natural passive immunity
d) Artificial passive immunity
Ans: b) Artificial active immunity
In malaria, the causative agent affects which cells in humans?
a) Red blood cells
b) White blood cells
c) Liver cells
d) Both a and c
Ans: d) Both a and c
Which of the following diseases is not transmitted by mosquitoes?
a) Dengue
b) Malaria
c) AIDS
d) Chikungunya
Ans: c) AIDS
During the preparation of the exam, there are different types of questions asked in different forms. The table given below contains the different patterns of questions asked in different exams.
Exam Type | Types of Questions Asked | Weightage |
| 5-6% | |
| 3-4% | |
| 2-3% |
It's hard to remember everything in a single go. We made the entire problem easy. Some of the tricks regarding human health and disease are given below which you can use to memorize the important points.
"DIA: Infectious, Autoimmune, Degenerative"
D: Infectious diseases (caused by pathogens)
I: Autoimmune diseases (immune system attacks the body)
A: Degenerative diseases (progressive deterioration of function)
"LIFE: Lifestyle, Inherited, Functional, Environmental"
L: Lifestyle choices (diet, exercise)
I: Inherited factors (genetic predisposition)
F: Functional limitations (chronic conditions affecting health)
E: Environmental factors (pollution, exposure)
"B-TEA: B cells, T cells, Eosinophils, Antibodies"
B: B cells (produce antibodies)
T: T cells (regulate immune responses)
E: Eosinophils (combat parasites and allergic reactions)
A: Antibodies (proteins that identify and neutralize pathogens)
"DIVA: Diet, Immunizations, Visits (doctor), Activities (physical)"
D: Healthy diet
I: Regular immunizations
V: Regular doctor visits for check-ups
A: Regular physical activity
"CAMP: Control, Adherence, Monitoring, Prevention"
C: Control symptoms (medication and lifestyle)
A: Adherence to treatment plans
M: Monitoring health status (regular check-ups)
P: Preventing complications (education and resources)
"VIP: Virus, Infection, Prevention"
V: Viral infections (e.g., influenza, COVID-19)
I: Bacterial infections (e.g., strep throat, tuberculosis)
P: Prevention strategies (handwashing, vaccination)
"HEAL: Healthy Eating, Exercise, Adequate Sleep, Limit Stress"
H: Healthy eating habits
E: Regular exercise
A: Getting enough sleep
L: Limiting stress through mindfulness and relaxation
"Fever, Pain, Swelling, Fatigue: "
F: Fever (indicates infection)
P: Pain (may signal injury or illness)
S: Swelling (could indicate inflammation)
F: Fatigue (may signal underlying health issues)
NCERT Biology textbook class 12 forms the base for learning about Human Health and Diseases. Further extended understanding of the concept can be done through "Trueman's Elementary Biology, Volume 2", which provides all essential explanations with practice questions. Another helpful book is "Pradeep's Biology" which provides proper explanations with solved examples. Other great videos, articles, and practice mock tests are available on the Careers360 website for this chapter.
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The key concepts in human health and disease are the types of diseases, common infectious diseases, infections, AIDS, cancer, etc.
Different ways of transmitting the virus are through sexual contact, blood transfusions of infected people and the use of one needle for more than one person.
The field of neoplasm - benign and malignant research is known as oncology.
The Human ImmunoDeficiency Virus (HIV) is responsible for causing AIDS.
Human diseases fall into two categories:
Congenital: A condition that has existed since birth
Acquired: Disease that occurs during a person's lifetime
Washing hands before meals protects one from pathogens that may transmit infectious diseases and helps the individual to be much healthier and cleaner.
Physical health can be influenced by key aspects: nutrition, physical activity, sleep, and hygiene.
Infectious diseases are Pathogens and contagious from one individual to another. On the other hand, non-infectious diseases are not transmitted from person to person. The latter is mostly caused by genetic or environmental factors and/or the result of bad habits in day-to-day life.
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