In this article, we are going to explore about semi-autonomous organelles. We will mainly focus on mitochondria and chloroplasts. Both these organelles are known to perform essential functions of cells ranging from generating energy to very specialized forms of metabolism.
Semi-autonomous organelles are membrane-bound structures within eukaryotic cells that contain their genetic material and are partially self-replicating. Though not fully autonomous compared to some other organelles like the ribosomes, they still get some functions from the cell, but with a touch of independence. Mitochondria and chloroplasts are two major examples of these kinds of organelles.
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Mitochondria are double membrane-bound cell organelles.
These are present both in plant cells and in animal cells.
These are commonly referred to as the powerhouse of the cell because they are responsible for the production of ATP during aerobic respiration.
Adenosine Triphosphate (ATP) is the main energy-carrying molecule in a cell. ATP represents the short-term stored energy of the cell.
Mitochondria are spherical or rod-shaped organelles that are surrounded by two membranes.
The outer membrane is smooth and contains special proteins called porins that allow easy diffusion of the particle. It is completely permeable to nutrient molecules, ions, ATPs etc.
The inner membrane has a complex structure. It shows infoldings called cristae (sing. crista) where the enzymes for the electron transport chain are present. It is highly selectively permeable.
The space between the outer and inner membrane is called the peri-mitochondrial or inter-mitochondrial space.
The most important function of the mitochondria is to produce energy in the form of ATPs during aerobic respiration. This process is called oxidative phosphorylation.
Mitochondria also serve as a storehouse of calcium ions.
They play an important role in the process of programmed cell death by removing the unwanted and excess cells during the development of an organism.
This diagram shows the various parts of mitochondria.
Chloroplasts are found in plant cells and some protists.
These are responsible for photosynthesis, converting sunlight into chemical energy (glucose).
They also have their own DNA (cpDNA).
Thylakoid Membrane is the inner membrane system inside the chloroplast where light-dependent photosynthesis reactions take place.
The thylakoids are stacked in structures called grana, thus increasing surface area to maximize the amount of light absorbed.
Stroma is the fluid-filled matrix outside the thylakoid membranes. The stroma contains enzymes that catalyze the light-independent reactions of photosynthesis (the Calvin cycle).
Chloroplasts are enveloped by a double membrane structure.
The outer membrane serves as a barrier between the chloroplast and the cytoplasm of the cell, and the inner one controls the passage of molecules into and out of the chloroplast.
Chloroplasts are primarily responsible for converting light energy into chemical energy in the form of glucose through the process of photosynthesis.
Chloroplasts assimilate carbon dioxide from the atmosphere during the Calvin cycle, using the ATP and NADPH generated during the light-dependent reactions.
This process leads to the synthesis of carbohydrates such as glucose, which serve as energy sources and building blocks for plant growth and development.
During photosynthesis, chloroplasts release oxygen as a byproduct of splitting water molecules.
This oxygen is crucial for aerobic respiration in plants and other organisms that depend on atmospheric oxygen for survival.
The evolutionary context is described below:
According to the Endosymbiotic Theory, mitochondria and chloroplasts represent ancient symbiotic relationships between early eukaryotic cells and engulfed eubacteria and cyanobacteria, respectively. Genetic evidence includes similarities of organelle DNA to that of bacteria. Independent replication and possession of bacterial-like DNA are further evidence for the evolutionary relationship of these organelles to free-living bacteria.
The diseases, resulting from mitochondrial DNA mutations, pose an immense challenge to the cells in energy production. Gene therapy and replacement of mitochondria are two excellent therapeutic possibilities for these disorders. Engineering chloroplasts, on the other hand, have extreme potential in agriculture and biotechnology.
Semi-autonomous organelles constitute a very important feature of cellular biology concerning the production of energy and initiating metabolic pathways. But they even have implications for a broader conceptual understanding of evolution. In effect, their structure, function, and importance help explain the complexity of life.
The video describing semi-autonomous organelles is given below:
Semi-autonomous organelles are membrane-bound cellular structures, including mitochondria and chloroplasts, with their own DNA that are capable of partial self-replication.
Mitochondria produce ATP by the process of oxidative phosphorylation, which involves the electron transport chain and ATP synthase located on the inner mitochondrial membranes.
Mitochondria deal with cellular respiration to produce ATP. On the other hand, chloroplasts perform photosynthesis to synthesize glucose and oxygen from light energy.
They are vital for energy production, and cellular metabolism, and also perform some specialised functions that are vitally important to the cell for survival and function.
Evidence includes a similarity of DNA between organelles and bacteria, independent replication of organelles, and structural similarity to bacteria, which supports the theory of the evolution of mitochondria and chloroplasts from an engulfed bacterium.
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