Transitional epithelium, one of the kinds of stratified epithelium, forms multiple layers of cells that look cuboidal if not under tension and squamous when stretched, showing characteristics of stretchiness and change of shape. The type of epithelium can provide possibilities of change in volume and pressure inside lining organs.
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Transitional epithelium plays a critical role in the urinary system. Lining the inner surface of the urinary bladder, the ureters, and part of the urethra, enables these organs to stretch without rupturing when they fill and again when they empty. Since it is elastic, it does not allow for the diffusion of urine into underlying tissues; hence, the integrity of the urinary tract is maintained while it undergoes volume changes. It is therefore important to both fluid retention and elimination.
The structure of transitional epithelium is described below-
The transitional epithelium consists of several layers of cells. Peripheral cells are large and dome-shaped. As one goes toward the basal layer, the cells decrease in size and become cuboidal or columnar.
Ability for stretching and change of shape: Probably one of the most distinct features of transitional epithelium is its ability to stretch and change shape. This allows organs like the bladder to dilate and contract without tearing.
While this epithelium stands in contrast to simple squamous or cuboidal epithelium, it can increase its volume. It is firmer and more elastic than any other epithelial tissue, most of which are stiff/rigid.
The location of transitional epithelium is described below-
Transitional epithelium will be lining the inside of the urinary bladder, ureters, and part of the urethra.
This kind of epithelium lining gives a protective covering, whereby leakage is not possible, hence saving the underlying tissues from damage by the urine in these organs.
The functions of transitional epithelium are described below-
Lining and forming a protective covering, saves underlying tissues from the corrosive action of urine.
This elasticity feature enables organs like the urinary bladder to distend to a large volume at times when it is full of urine and contract when empty.
The tight junctions seal the cells together and hence act as a barrier to prevent leakage of urine in the surrounding tissues.
Transitional epithelium acts like a stretchable protective lining in the volume changes of urine in the urinary bladder and other parts of the urinary tract.
The urinary bladder, the ureters and the part of the urethra are lined with transitional epithelium.
Unique features of this transitional epithelium, unlike the rest of the epithelial tissue, are its stretchability and change of shape, thus from cuboidal to squamous depending on the volume of urine.
Common diseases include cystitis and cancer, an inflammation in the bladder.
The transitional epithelium is composed of multiple layers of paving cells that line the surface and can change shape. Surface cells are large and dome-shaped when the bladder is empty and they become flattened when the bladder is full.
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