Correct Answer: itai-itai

Solution : The correct answer is itai-itai .

Excess amounts of cadmium in the human body can damage the person's lungs and cause death; the itai-itai disease is caused by cadmium. The name Itai-itai was given by the Japanese in 1912. Excess amounts of cadmium can cause softening of the bones and kidney failure, which may result in the death of a person.