No as per the IISER eligibility criteria, you need to give IISER aptitude test with all the four subjects that is Physics, Chemistry, Mathematics and Biology. There will be 15 questions from each sections. 3 positive marks for each correct answer and negative marking of -1 for each wrong answer so you can try to choose wisely if you are a PCM student.
Refer to the link below for more detailed information about the same...
https://engineering.careers360.com/exams/iiser-aptitude-test
Best wishes. Thank you.
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