Hi Aspirant,
Yes, you can take commerce after your 11 and 12th with Science. But in that case you must have had Mathematics as a subject. Now you can go for degree courses like BBA, BCom, BCom(Hons), etc. Actually the eligibility for studying a degree course in Commerce most of the time says that candidate should have passed 10+2 Exams with a 50% aggregate of the total marks. And in few cases some private universities have their entrance exams.
For more information regarding the degrees in Commerce, eligibility criteria, colleges,etc refer the link below,
https://www.careers360.com/courses/commerce-course
Hope this helps.
All the best!!!
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