Correct Answer: General

Solution : The correct choice is the fourth option.

The word that can substitute for the given group of words "affecting all or most people, places, things, etc." is general.

The word refers to something widespread, common, or universal.

The meanings of the other options are as follows:

Particular: This word refers to something specific or individual, and it is the opposite of the intended meaning.

Pertain: This word means to relate to or have relevance to a particular subject or situation, and it does not convey the sense of affecting all or most.

Genre: This word refers to a category or type of artistic, musical, or literary composition characterised by a particular style, form, or content. It does not capture the idea of affecting all or most.

Therefore, general is the most appropriate word to substitute for the given group of words.