See mathematics and statistics are involved in biotechnology in order to analyse trends and predict scientific outcomes from systems. So you need to know mathematics to some extent. Now in BTech most of the universities have comprehensive Mathematical Methods papers in the first and the second year. From third year the course mostly tend to the core subjects. So for atleast two year you have to deal with mathematics as course in your BTech curriculum.
To know more about the BTech in Biotechnology visit the link below:
https://www.careers360.com/courses/b-tech-in-biotechnology
I hope this answer helps. All the very best for your future endeavors!
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