Hey,
You can appy for IISER in your final year of graduation but you need to meet few requirements.
The eligibility for Master's in physics from IISER should be,
-a minimum of 60% in your graduation
-should have appeared for IIT JAM and his or her rank should be under 500 .
Below is the link for eligibility bof IISER Pune,
http://www.iiserpune.ac.in/admissions/int-phd-programme
As you have not mentioned a particular IISER, so I have given you the reference of IISER Pune.
Hope that helps.
Thank you.
Regular exam updates, QnA, Predictors, College Applications & E-books now on your Mobile