Yes, absolutely! If you are a student of PCM, you are not required to take biology in +2 to appear in the CUET exam. If you want to do B.Sc Physics at any IISER, you are free to do so even without having Biology as one of your subjects in class XIIth.
Hope I have answered your question. All the best!
Regular exam updates, QnA, Predictors, College Applications & E-books now on your Mobile