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To be eligible to appear for NEET UG a candidate must have passed 10+2 with Biology/Biotechnology, Physics, Chemistry and English from a recognized board. The category wise minimum percentage of marks that a candidate need to score in Biology/Biotechnology, Physics and Chemistry taken together (practical and theory) is as follows
If you haven't studied Biology/Biotechnology you can enroll in open schooling such as NIOS and pass in either Biology or Biotechnology to be eligible to appear for NEET UG provided you must score the required percentage of marks as mentioned above based on your category. You do not have to change the stream.
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If Biology or Biotechnology was not as one of your main Subjects then you are not eligible for NEET 2021. In order to be eligible for NEET you have to fill up form of 12th once again as Physics Chemistry Biology and English as your main subjects. These four Subjects are mandatory for NEET.
To know more about NEET, please go through this link
https://www.google.com/amp/s/medicine.careers360.com/articles/neet-eligibility-criteria/amp
Good Luck.
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