The cutoff varies every year depending on the difficulty level of the question paper in that year.

However, considering what happened in 2018, you should score at least 600 marks if you are aiming for an open category seat.

For detailed information about CMC Vellore, you can read How can I get admission in CMC Vellore? [Every question answered] . This article answers all your questions related to CMC Vellore and it's admission.