I want to opt bsc life science. Can i use biology, physical education and painting/english in best four??
The best of four methodology of calculation is entirely dependent on the instruction of the college or university, you wish to take admission in. Now if you see for every subject there are some compulsory subject you should keep in your best four. English is one of the compulsory subject you have to keep in best 4. Now every university have different eligibility for every subject. For example, if anyone wants to get admitted in BSc Physics, the best four must have Physics and Mathematics but some universities only have the eligibility to keep physics compulsorily. Thus it can't be said what you can take or can't based on arbitrary conceptions. Its entirely dependent on your university/college norms.
If you aren't sure I would recommend you to contact the college/university admission cell and they will surely assist you.
I hope this answer helps. All the very best for your future endeavors!