Yes if you have passed your 10+2 science from UP board then also you are eligible to give the MHT - CET exam. But here in this situation you will be classified as a All India Category Candidate and only be eligible for seats in private colleges of Maharashtra. Also you must have Physics and Mathematics as compulsory subjects along with any one of Biotechnology/Biology/Chemistry/Technical/Vocational subjects.

There is another category where you could be eligible as a Maharashtra state candidate

:

1.Type B -fathers or mother is domiciled in Maharashtra & have domicile certificate.

2.Type C-Candidates,  whose fathers or mother is a government employee of India & posted in Maharashtra State before last date of submission of application for CAP.

3.Type D-Candidates, whose fathers or mother is an employee or retired employee of Government of Maharashtra.

If you belong to any category above you will be eligible to opt government colleges too , otherwise you are a All India Candidate.

Hope you like the answer!