Hello there!
The comparison is tough as both IITs and IISC give real good scope for research and higher learning.
Although people generally move towards IISC as its the hub for researchers and research.
Although entry to these institutions is via IIT-JAM and post counseling only one can know if they are getting into IIT or IISC.
So prepare well.
Good Luck!

IISc Bangalore

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