Question : In the context of substance use disorders, tolerance refers to:
Option 1: The social acceptance of substance use
Option 2: The legal limits for substance consumption
Option 3: The need to increase the amount of substance to achieve the same effect
Option 4: The ability to use substances without negative consequences
Correct Answer: The need to increase the amount of substance to achieve the same effect
Solution : In the context of substance use disorders, tolerance refers to the need to increase the amount of substance consumed to achieve the same effect or feeling that was initially experienced with smaller amounts. It is a sign of physical dependence on the substance.