Hello,
The eligibility criteria for admission into IISER is:-
which means that there is no longtterm students scope to be eligible for iiser. it's just two year and two attempts.
There 7 performance criteria which are described by the board and how the marks will be considered is explained stepwise. please follow the link:-
http://www.iiseradmission.in/index.php/pages/eligibility
Hope it helps!
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