Admission in MSC bioinformatics program at an IIT is through the Joint Admission Test for Masters (JAM). JAM is a nationwide entrance exam that's held annually for admission to post-graduate science programs at various institutions in India.
You can also apply to IISERs and JNCASR Bangalore for Integrated PhD. Course through jam.
Other exams which are accepted for MSc bioinformatics are Gate,jee advanced and some universities like jnu accept CUET-PG or GAT-B score.
To excel in the JAM exam, you should have a strong understanding of the fundamental concepts in biology, chemistry, mathematics, and physics.
This link will help you in preparation and exam details
https://university.careers360.com/exams/jam
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