Hello,

Hope you are doing well!

There is bit of difference in both the courses. Syllabus of MCA focuses on the practical knowledge of the computer science like computer languages, coding, application software, etc.

Whereas in Msc, you will study more about the theoretical part of hardware and softwares.

Job opportunities in both the courses are different. Market demand for MCA graduate are higher than that of msc graduate.

You can check details about both the courses here,

https://www.careers360.com/courses/mca-master-of-computer-applications/amp

https://www.careers360.com/courses/msc-in-computer-science

Hope this will help.