With an AIR (All India Rank) of 22,000 in NEET PG, getting a DNB (Diplomate of National Board) seat in the General category can be challenging but possible, especially if you're flexible with your preferences for location and institutions.

Here are some insights:

1. **Lower-Tier Government Hospitals and Institutions**: While top-tier institutions and central government hospitals might be difficult to secure, you may still find seats available in DNB programs at smaller government hospitals, district hospitals, or hospitals in less popular locations. These institutions often have vacancies in the later rounds of counseling.

2. **Specialization Consideration**: If you're set on DNB General Medicine, competition is tougher. However, if you're open to other specializations or less sought-after branches, your chances improve significantly.

3. **Rounds of Counseling**: Keep an eye on the second and mop-up rounds of counseling. Seats in government colleges or hospitals that weren't filled in earlier rounds might become available, and your rank could then be competitive.

4. **State Quota**: If your domicile state offers DNB seats under state quota counseling, your chances might improve. Each state has different cutoff trends, so check your state's specific counseling process.

To maximize your chances, participate in all counseling rounds, stay updated with cutoff trends, and consider less popular locations or institutions.