My Signature in self Attested document in DU Registeration process is different from original signature uploaded will it pose any problem for me during Admission process
Nope! It will not cause any problem but it is always preferable for any examination that you should write the full name as your signature. Now if you have done some twist in your signature then it doesn't matter provided you should be able to write the signature if required later wise. Although let me assure you that its not a bank and no one will be testing your signature to higher precession. So don't worry about it.
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https://www.careers360.com/university/university-of-delhi-delhi
I hope this answer helps. All the very best for your future endeavors!