parital cells secrete acid , Hcl but still why do the ap appear pink in histology slides not blue why ,. what makes them to take up acidic stain. please answer
Hello aspirant,
Parietal cells are epithelial cells in the stomach that secrete HCl. The gastric fundal epithelium has long tubular glands that are lined up pink- staining parietal cells as well as mucus cells. The cells stain basophilic upon H&E staining due to the large proportion of rough endoplasmic reticulum in its cytoplasm. Gastric chief cells are generally located deep in the mucosal layer of the stomach lining, in the fundus, and body of the stomach. That's why it appears pink in color.
Thank you