For both ISRO , DRDO you have to give gate
In gate exam it's depends on which department you are. There are many recruitment but different course,
In DRDO the vacancy come soon, Students having a validGATE 2021score from the year 2021/2020/2019 are eligible to apply for DRDO Scientist B recruitment.
For official notice you can visit there oficial site (
https://rac.gov.in
Minimum 80% aggregate marks in your degree,
Selection Criteria for DRDO recruitment through GATE 2021/2020/2019

For Part I -80% weightage will be given to the descriptive examination and 20% weightage to personal interview.

For Part II -80% weightage will be given to the GATE scores and 20% weightage to personal interview

In ISRO it is really hard you have to score very good. Or excellent , there interview is quite hard .
Click Hereto download the latest ISRO recruitment 2020-21 notification. As per there eligibility criteria aggregate minimum of 65% marks or CGPA of 6.84 on a scale of 10. In ISRO. Candidate have minimum of 60% in the interview process will be eligible for consideration for empanelment in the selection panel.
You can visit there career or job recruitment notification https://www.isro.gov.in/careers

For more information you can visit here
https://engineering.careers360.com/articles/isro-recruitment
https://engineering.careers360.com/articles/drdo-recruitment-through-gate

Thank you. I hope this answer helps you.

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