Correct Answer: destroy

Solution : The correct choice is the fourth option.

Explanation:
The antonym of "establish" is "destroy". To establish means to create or set up, while to destroy means to ruin or demolish.

The meanings of the other options are as follows:

• Institute means to establish or set up.
• Constitute means to form or make up; to establish as a part.
• Start means to begin or commence.

Therefore, the correct answer is d estroy.