Correct Answer: Tiny

Solution : The correct choice is the second option.

Explanation : Tiny specifically refers to something that is extremely small in size or amount, making it the most fitting substitute for " something that is very small or little ".
The meanings of the other options are as follows:

• Few means a small number of items or a small amount of something.
• Thin refers to having a small distance between opposite sides, often describing something slim or narrow.
• Slender means slim and graceful, often used to describe something with a delicate or elegant appearance.

Therefore, the correct answer is tiny.