Hello Aspirant,
I hope you are doing well.
It is not compulsory to appear in MHTCET PCB and PCM for both of the exams if you have paid and registered for both individually. You may choose to give both or appear in any one of them. PCM is for engineering admission, PCB/ PCM score is for pharma d and B. Pharm admission. But if you have chosen PCMB then you cannot change it to just PCB.
I hope this helps.
Good Luck
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