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The presence of histone H ₁ implies that nucleosomes have completed their synthesis. Histone has a positive moiety that binds to DNA that is negatively charged. A single DNA molecule of tremendous length exists in the eukaryotic chromosome. The DNA is linked to a vast number of protein molecules called chromatin. When histone H ₁ binds to a nucleoside, it means the DNA has been condensed into a chromatin fibre.