Correct Answer: Nitrous oxide, Chloroform

Solution : The correct option is Nitrous oxide, Chloroform.

One of the first anesthetics was nitrous oxide. It is a gas that has no color or smell. It is not appropriate for severe surgical anesthesia, while it can cause a mild sedative and analgesic condition. In some dental treatments and as part of balanced anesthetic approaches, it is still employed.  In the late 19th and early 20th centuries, the general anesthetic chloroform was often employed. However, due to safety concerns, particularly its potential to cause liver and renal damage, its use has mostly been discontinued.