We are aware that our bodies obey the instructions provided by our genes as they grow. When a physical component grows differently from how it should, it's because the gene from which it gets its instructions has altered. The many genes that contribute to the characteristics of all forms of OFDS are still being studied by researchers. Since the gene causing Type I OFD is known, a patient's blood may be examined to discover if the OFD1 gene has changed. Since several characteristics of the OFDS categories overlap, this can aid in ruling out an alternative diagnosis.