Dear,
Typhoid is a bacterial infection that can lead to a high fever, diarrhea, and vomiting. It can be fatal. It is caused by the bacteria Salmonella typhi. The infection is often passed on through contaminated food and drinking water, and it is more prevalent in places where handwashing is less frequent. It is usually between seven and fourteen days, but can be as short as three days, or as long as 30 days. Untreated, the illness usually lasts for three to four weeks, but may be longer in a small number of cases. Symptoms vary from mild to severe and life-threatening.
Chloramphenicol has been the antibiotic of choice for patients with typhoid fever for more than 30 years, although ampicillin and cotrimoxazole have been introduced as alternatives, they have side effects, and disadvantages of frequent administration and long duration of treatment similar to chloramphenicol therapy.
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