Question : Who first observed ribosomes in the mid-1950s and described them as small particles in the cytoplasm that were preferentially attached to the endoplasmic reticulum membrane?
Option 1: Ernst Abbe
Option 2: Albert Kolliker
Option 3: Carl Zeiss
Option 4: George E. Palade
Correct Answer: George E. Palade
Solution : The correct answer is George E . Palade .
George E. Palade discovered ribosomes in 1955. He identified them as small particles present in the cytoplasm, which often remain associated with the endoplasmic reticulum. They are specialised cell organelles which are found in both prokaryotic and eukaryotic cells. He discovered it using an electron microscope. He was awarded the Nobel Prize in Physiology or Medicine in 1974 for his innovations in electron microscopy and cell fractionation, which together laid the foundations of modern molecular cell biology.
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