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Quick Facts
| Medium Of Instructions | Mode Of Learning | Mode Of Delivery |
|---|---|---|
| English | Self Study | Video and Text Based |
Course Overview
This course on Enzymology will enable you to analyse scientific phenomena that enzymes form a part of. This knowledge will, in turn, help you to function effectively at both the academic and professional levels. This branch of biochemistry deals with the function of enzymes and their formation into their state of origin.
As a multidisciplinary research field, Enzymology combines the fields of microbiology, biochemistry, molecular genetics, biology, and molecular biology. Hence, this subject is suitable for candidates belonging to various disciplines. The development in this subject is reflected in the advancement of the tools used by enzymologists.
And this has created an increased demand for this subject. Tasks like genomic sequencing can be conducted with gene synthesis that is available at cheap prices. And this allows enzymologists to study any enzyme and produce pure proteins without much effort.
Thorough knowledge of Enzymology can help you in building a career in biology as well as the other domains such as medical and environmental sciences. The course instructor has decades of experience in teaching this subject to the students belonging to the science department. This course will, therefore, help you in building a strong knowledge base on this subject.
The Highlights
- Online mode of training
- Duration of 12 weeks
- Granting of a certificate post-registration
- Course content prepared by a subject matter expert
- Wide range of career options with the knowledge of this subject
- Preparation through quizzes and tests
- Certification that is recognised by the Government
- Interactive classes
- Access to course materials without any charges
- Obtaining of Swayam certificate after completing a proctored exam
Programme Offerings
- Online training
- Free course materials
- government certification
- Self explanatory illustrations
Courses and Certificate Fees
| Certificate Availability | Certificate Providing Authority |
|---|---|
| yes | Kashmir University |
Eligibility Criteria
There are no prerequisites to join the course. Any student who is willing to take this undergraduate course to enhance knowledge and skills can be a part of this.
Certification Qualifying Details
The certificate is given out to students who register themselves for the proctored exam and pay the exam fee. The exam is held in-person at specific locations. Scoring a minimum of 70 percent in this exam is one of the eligibility criteria for the certificate. Another criterion is that you score at least 30 percent in the internal assessment. You will receive an e-certificate post declaration of results.
What you will learn
This course on Enzymology by Swayam will give:
- Providing you with in-depth knowledge of enzymes and their mechanisms.
- You will be taught on the methods of producing enzymes in large quantities, the various types of enzymes, application of soluble enzymes, protein folding, protein sequencing, as well as a qualitative description of sequential models.
- Some of the other topics that this course will cover are enzyme active sites, Isozymes with their significance, transition state theories, enzyme kinetics, and protein folding.
- An understanding of these along with the other topics will enable you to get familiar with the functions of enzymes.
Who it is for
Anybody can benefit from this course on Enzymology as the course goes beyond the field of biology. Professionals in the healthcare field as well as medical professionals can pursue this course to surge ahead in their careers.
Admission Details
Enrollment in the program can be obtained by clicking on the Join option. You will be directed to a page where you will have to fill in your details. You can then start accessing the course materials and begin the journey of knowledge.
Application Details
Application for the course can be made by creating an account on the portal. You will need to fill in your details and verify your email address by clicking on the link sent to your inbox. Once your account is created, you can click on the Join option to proceed further. All course-related details are available on the portal itself.
The Syllabus
Enzymes
- Nomenclature and classification of enzymes Holoenzyme
- apoenzyme
- cofactors
- coenzyme
- prosthetic groups
- metallo enzymes
- monomeric and oligomeric enzymes Activation energy and transition state theory
- enzyme activity
- specific activity
- common features of active sites
- enzyme specificity: types and theories Factors affecting enzyme activity
- E, S, temp and pH
- Role of NAD+ NADP+
- Folic acid and Vit.
- B12 as biocatalysts
- FMN/FAD
- Coenzyme A
- Lipoic acid
- biotin
- tetrahydrofolate and metal ions as biocatalysts
- Role of thiamine pyrophosphate
- pyridoxal phosphate as biocatalysts
- Biocatalysts from extreme thermophillic and hyperthermophilic archea and bacteria
- Enzyme substrate complex: Concept of E-S complex,
- binding sites
- active site
- specificity
- kinetics of enzyme activity
- Michaelis- Menten equation and its derivation
- Different plots for the determination of KM and Vmax and their physiological significance
- Two substrate reactions (random, ordered and ping pong mechanisms)
- enzyme inhibition
- types of inhibition
- determination of Ki
- suicide inhibitor
- Qualitative description of concerted and sequential models
- Negative cooperativity
- Half site reactivity
- Enzyme regulation: Product inhibition,
- feedback control
- covalent modification
- Enzyme- enzyme interaction
- protein ligand binding
- Measurement analysis of binding isotherm
- cooperativity
- Hill and Scatchard plots
- Kinetics of allosteric enzymes
- Allosteric enzymes with special reference to aspartate transcarbomylase and posphofructokinase
- Mechanism of enzyme action
- general mechanistic principle
- Techniques for studying mechanism of action
- Factors associated with catalytic efficiency
- proximity
- orientation and distortion of strain
- Collision and transition state theories
- significance of activation energy and free energy
- Acid base
- Nucleophilic and covalent catalysis
- Isolation
- crystallization and purification of enzymes
- Test of homogeneity of enzyme preparation
- methods of enzyme analysis
- Detailed view of techniques for studying Enzyme assay
- Chemical modification of active site groups
- chymotrypsin
- Lysozyme
- RNase
- Carboxypeptidase
- GPDH
- Aldolase
- alcohol dehydrogenase
- 5 Subjective
- Zymogens and their activation (proteaseses and prothrombin)
- Isozymes: Multiple forms of enzymes with special reference to lactate dehydrogenase
- Multienzyme complexes
- Ribozymes
- Multifunctional enzymes e.g., fatty acid synthase
- Enzyme technology: Methods for large scale production of enzymes
- immobilized enzymes and their comparison with soluble enzymes
- Methods of immobilization of enzymes
- immobilized enzyme reactors
- Application of immobilized and soluble enzymesin health and industry
- application to fundamental studies of biochemistry
- enzyme electrodes
- Thermal stability and catalytic efficiency of enzyme
- site directed mutagenesis and enzyme engineering-selected examples
- 5 Subjective
- Delivery system for protein pharmaceuticals,
- structure function relationship in enzymes,
- structural motifs and enzyme evolution
- Methods of protein sequencing
- Methods for analysis of secondary and tertiary structure of enzymes
- Protein folding in vitro and in vivo
Evaluation process
A certificate for the course can be obtained only after you register yourself for the proctored exam against the payment of an exam fee. You need to score at least 70 percent in this exam along with 30 percent in your in-course assessment to qualify for the certificate.
Instructors
Kashmir University Frequently Asked Questions (FAQ's)
Courses with Swayam are available free of cost unless the candidate wants to receive the Swayam certificate. The course is specially designed to enable students’ function in the absence of a physical structure. Hence, the course content will allow you to acquire sufficient knowledge on the subject and find a wide range of career options.
You will be provided with online lectures delivered by an expert faculty. You will get a list of books that you can refer to. You will also have ample MCQs, self-explanatory illustrations, and short answer questions to prepare effectively on this subject.
Swayam courses are recognised by the Government as well as the educational institutions. The contents are designed by top-rated education providers and are accepted by the recruiting bodies as well.
Some of the universities recognise Swayam courses as credit-eligible. In such situations, the certificate can be used to earn academic credit and obtain a higher education.
To take the certification exam you need to register on the portal and pay the proctored exam fee. Registration dates are announced on the portal itself. The exam is conducted in-person at designated locations.