Correct Answer: Lack of blood supply to the heart itself

Solution : The correct option is Lack of blood supply to the heart itself.

A heart attack, also known as a myocardial infarction (MI), happens when blood supply to a portion of the heart muscle is suddenly cut off. The development of a blood clot in one of the coronary arteries, which deliver oxygen and nutrients to the heart, is generally the reason of this obstruction. The development of coronary artery disease (CAD), a condition in which the coronary arteries become restricted or obstructed owing to the formation of fatty deposits termed plaque, is the most common underlying cause of a heart attack.